Comparison of LDH-5 and total LDH levels in NHL patient serum.

Abstract

<p>(A) ROC analysis of LDH-5 showed that the cutoff value set at 9.1% gives the best diagnostic efficiency (AUC = 0.788, n = 529). (B) The sensitivity and specificity for NHL diagnosis were 53.4% (142/266) and 74.6% (196/263) at the LDH-5 cutoff value (9.1%), respectively. (C) Serum LDH-5 concentration ≥9.1% has more positive results than total LDH ≥250 IU/L in all NHL patients (n = 266) and patients with advanced NHL (III+IV, n = 122). *<i>P</i><0.05; **<i>P</i><0.01.</p