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Developing Pd(II) Catalyzed Double sp<sup>3</sup> C–H Alkoxylation for Synthesis of Symmetric and Unsymmetric Acetals

Abstract

An effective Pd­(II) catalyzed double unactivated C­(sp<sup>3</sup>)–H alkoxylation has been developed to prepare both symmetric and unsymmetric acetals. This new reaction demonstrates good functional group tolerance, excellent reactivity, and high yields. A variety of novel acetals can be readily accessed via this new method

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The Francis Crick Institute

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Last time updated on 12/02/2018

This paper was published in The Francis Crick Institute.

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