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Temporal dynamics of CSF vesicle miRNAs.
Abstract
<p>A. miRNA microarray heat-map of CSF vesicle content from patients less than 2 years or greater than 70 years where red is higher expression and green is lower expression. B. Rank expression of miRNAs based on microarray probe intensity. Red is microarray data from patients less than 2 years and black is from patients greater than 70 years. C. Log(<sub>2</sub>) signal of the most abundant miRNAs. D. Hierarchical clustering of miRNA microarrays at different ages. E. Venn diagram of high abundance or (F.) low abundance miRNAs at different ages.</p- Image
- Figure
- Biological Sciences
- CSF EVs encapsulated miRNAs
- RNA sequencing
- Cerebrospinal Fluid Extracellular Vesicles Undergo Age Dependent Declines
- CSF EV concentrations
- EV RNA content
- EV exchange
- Brain development
- choroid plexus epithelial cells
- intercellular communication
- CSF EV content
- Cerebrospinal fluid
- Extracellular Vesicles
- miRNA microarray analysis