Distribution of CD90 in PDAC of early and late stages evaluated by immunofluorescence staining (<i>green</i>).

Abstract

<p>DAPI counterstaining was used to visualize nuclei (<i>blue</i>). In early-stage PDACs, CD90 is abundantly expressed on stromal cells, including activated fibroblasts and vascular cells which form the basis for blood vessels (shown in square). Membrane expression of CD90 on the apical cell surface was rarely observed in malignant ducts in late-stage PDACs (marked with a star or arrow). Expression was also observed on endothelial cells (in red circle). Scale bars  = 100 µm.</p