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The expression levels of CD80 (A), CD86 (B) and HLA-DR (C) on various regimens treated iDCs.
Abstract
<p>The iDCs were treated with mock, BCG-CS-NPs, UVI-DENV (1, 3 and 10 μg) and DNV (1, 3 and 10 μg) for 24, 48 and 72 h. The expressions of CD80, CD86 and HLA-DR were determined as the mean fluorescence intensity (MFI) by flow cytometry. <sup>a</sup> indicates significant difference between mock- and adjuvant-treated culture. *,** and *** indicate significant difference in MFI level of CD80, CD86 and HLA-DR between DNV and UVI-DENV antigen at 1 μg, 3 μg and 10 μg, respectively.</p- Image
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- loading efficacies
- thp
- emulsion polymerization method
- DENV infection
- idc
- component
- cationic surface properties
- bcg
- delivery system
- chitosan nanoparticles
- DENV infections
- dengue vaccines
- scanning electron microscope
- chemokine productions
- Human Dendritic Cells Dengue viruses
- novel dengue nanovaccine
- immunogenic properties
- DNV stimulation
- DCs maturation markers
- Dendritic cells