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Asymmetric Synthesis of Cyclobutanones: Synthesis of Cyclobut-G
Abstract
A simple, efficient, and stereoselective approach has been developed for obtaining chiral cis- and trans-disubstituted cyclobutanones from readily available alkyl- and functionalized alkyl-substituted enol ethers. The usefulness of these cyclobutanones is illustrated by an enantioselective synthesis of cyclobut-G (Lobucavir)- Text
- Journal contribution
- Biophysics
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- Physical Sciences not elsewhere classified
- Cyclobutanone
- functionalized
- usefulness
- ether
- cyclobutanone
- chiral cis
- Asymmetric Synthesis
- stereoselective approach
- Lobucavir
- enantioselective synthesis
- alkyl
- enol