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Additional file 11: Figure S7. of Evaluation of logistic regression models and effect of covariates for case–control study in RNA-Seq analysis

Abstract

Q-Q plots of the HD Analyses. Figure S7 exhibits the Q-Q plots from the HD analysis adjusting for age at death and RIN from DESeq2 (A), and Classical (B), Bayes (C), and Firth’s (D) Logistic regressions. Each regression method contains three different ways of calculating p-values (Original, DA, and Perm). “Original” p-values (Blue dots) are estimated from asymptotic distribution. “DA” p-values (Black dots) are evaluated from data adaptive asymptotic distribution using 1,000 permutations. “Perm” p-values (Yellow dots) are calculated using 10,000 permutations. (PNG 157 kb

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The Francis Crick Institute

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Last time updated on 12/02/2018

This paper was published in The Francis Crick Institute.

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