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Limit of detection of LAMP reactions using the high throughput sample processing system.
Abstract
Representative amplifications experiments using serial dilutions of samples of known parasitaemia (quantified using the WHO International Standard as calibrator). Mean time to turbidity in minutes as follows: 10,000 p/μL = 17.5; 1,000 p/μL = 18.5; 100 p/μL = 19.4; 10 p/μL = 21.3; 1 p/μL = 22.9.</p- Image
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- Medicine
- Microbiology
- Cell Biology
- Genetics
- Molecular Biology
- Biotechnology
- Evolutionary Biology
- Immunology
- Cancer
- Infectious Diseases
- WB
- sub-microscopic malaria infections
- 94 samples
- scale population screening
- WB-HTP-LAMP
- malaria elimination campaigns
- PCR
- sensitivity
- malaria LAMP kits
- HTP-LAMP system
- 699 samples
- DBS HTP-LAMP
- throughput loop-mediated
- DBS-HTP-LAMP
- specificity
- Eiken malaria LAMP kit
- HTP system utilised
- CI
- parasite densities
- blood spots
- infection status
- malaria Background
- performance
- sample processing system
- sample processing
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Last time updated on 12/02/2018
This paper was published in The Francis Crick Institute.
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