Validation of common DEGs in BEAS-C and derivatives cells treated with pharmacological inhibitors of the PI3K/AKT pathway.

Abstract

<p><b>A)</b> Analysis of 7 common DEGs enriched in BioFunctions in BEAS-C and derivatives. Bars are mean±SD of 3 independent experiments performed in triplicate. Statistical analysis was performed by One-way ANOVA test and Dunnett's test for each gene. p-values were indicated in the figure. <b>B)</b> BEAS-C cells and derivatives were treated for 24 hours with the indicated doses of LY294002. Graphs show mRNA levels of the indicated genes in BEAS-C cells and derivatives. Bars are mean±SD of 3 independent experiments conducted in triplicate. Statistical analysis was performed by <i>t-</i>test. p-values as indicated in the figure.</p