Elevated zero maze (EZM) analysis of mice at 3–5 months of age (young adult).

Abstract

<p>Age- and strain-matched WT (n = 16) mice were evaluated in parallel with NrbKO (n = 9) and SpKO (n = 8) mice. (A) The percentage of time spent in the open versus closed regions of the EZM during the entire trial time. (B) Total distance traveled during the entire EZM trial time. (C) Entries into the open and closed area of EZM during the trial. Data are mean ± SEM. **, <i>p</i><0.01, NrbKO <i>vs</i>. WT by Student’s <i>t</i> test.</p