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Top 30 genes significantly more highly expressed in the RPE compared to the IE.
Abstract
<p>The genes that are in bold were shown to be enriched in the human RPE [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182983#pone.0182983.ref026" target="_blank">26</a>]. Asterisks mark the genes that might be present in our dataset by contamination of the mRNA on the photoreceptor-RPE interface or may be expressed to some extent in both adjacent cell layers (also see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0182983#sec021" target="_blank">Materials and methods</a>).</p- Dataset
- Dataset
- Biochemistry
- Medicine
- Cell Biology
- Genetics
- Molecular Biology
- Neuroscience
- Immunology
- Developmental Biology
- Marine Biology
- Cancer
- Infectious Diseases
- autologous iris epithelial cell transdifferentiation
- aryl hydrocarbon receptor
- donor eyes
- retinitis pigmentosa
- retinol biosynthesis
- iris epithelium
- age-related macular degeneration
- network level
- Comparative gene expression study
- vision loss
- pathway analysis
- detoxification state
- future research
- pigment epithelium
- future replacement therapy
- IE cells
- knowledge database Ingenuity
- neuro-epithelial cell functions
- laser dissection microscopy
- transcriptional variation
- pigment epithelium Background
- RPE
- gene expression profiles
- whole-genome expression
- expression profiles
- 44 k Agilent