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The 23S rRNA helix 35 is the substrate of RlmCD.

Abstract

<p>(A) Secondary structures of the 18-mer RNA fragments of the <i>S</i>. <i>pneumoniae</i> (left) and <i>E</i>.<i>coli</i> (right) 23S rRNA helix 35. (B) In-vitro methyltransferase assay of RlmCD. The left three columns represent the methyl transfer activities of the wild-type RlmCD or its mutants toward rRNA-h35. The right three columns represent the methyl transfer activities of the wild-type RlmCD toward the different derivatives of rRNA-h35 (U747A, U747G, and U747C).</p

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The Francis Crick Institute

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Last time updated on 12/02/2018

This paper was published in The Francis Crick Institute.

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