Purpose of review
The interest in quotidian hemodialysis has increased
further after the HEMO study reported that high-dose
thrice-weekly hemodialysis failed to improve clinical
outcomes. This, in combination with a significant volume of
newly published data, made a review of the topic of
quotidian hemodialysis timely.
Recent findings
The published research has revealed further evidence of
cardiovascular and quality-of-life improvements as well as
financial benefits with quotidian hemodialysis. Accrued
worldwide experience has confirmed the previously
published benefits of quotidian hemodialysis. There has
been a significant effort by industry to produce
patient-friendly machines for home hemodialysis. Reports
on the use of daily hemodialysis and hemodiafiltration in
children have appeared. An international registry of patients
on quotidian hemodialysis has been created. The need
for modification of the funding mechanisms and the lack of
prospective randomized controlled studies on quotidian
hemodialysis led to the funding of such studies by the
National Institutes of Health in collaboration with Centers
for Medicare and Medicaid services to be completed by
2008. The proper funding for daily home hemodialysis was
secured in the province of British Columbia, Canada, and is
under consideration elsewhere.
Summary
There is increasing evidence confirming that quotidian
hemodialysis improves clinical outcomes in a cost-efficient
manner. Provided that the reimbursement issues are
resolved these modalities may be utilized extensively at
home as well as in the in-center facilities. The revitalization
of home hemodialysis will compensate for the decline in
utilization of continuous ambulatory peritoneal dialysis and
the nursing shortage encountered in most countries
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