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Impact of low-thermal-injury devices on margin status in laryngeal cancer. An experimental ex vivo study

By Giuditta Mannelli, Giuseppe Meccariello, Alberto Deganello, Vincenza Maio, Daniela Massi and Oreste Gallo


We conducted a prospective study on 10 excised larynges from patients affected by advanced laryngeal cancer, to assess the thermal-effect due to surgical incisions made at standard distance by using: scalpel, CO2 Laser, harmonic scalpel and electrocautery. Upon histopathological examination, thermal damage (Surgical Artifact, SA), tissue lost/retraction (Shrinkage, S), and tissue alterations were compared for each instrument

Topics: laryngeal cancer
Publisher: 'Elsevier BV'
Year: 2014
DOI identifier: 10.1016/j.oraloncology.2013.10.001
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