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Outbreak of Fatal Childhood Lead Poisoning Related to Artisanal Gold Mining in Northwestern Nigeria, 2010.

By C A Dooyema, A Neri, Y-C Lo, J Durant, P I Dargan, T Swarthout, O Biya, S O Gidado, S Haladu, N Sani-Gwarzo, P M Nguku, H Akpan, S Idris, A M Bashir and M J Brown

Abstract

Background: In May 2010, a team of national and international organizations was assembled to investigate children's deaths due to lead poisoning in villages in northwestern Nigeria. Objectives: To determine the cause of the childhood lead poisoning outbreak, investigate risk factors for child mortality, and identify children aged <5 years in need of emergency chelation therapy for lead poisoning. Methods: We administered a cross-sectional, door-to-door questionnaire in two affected villages, collected blood from children aged 2-59 months, and soil samples from family compounds. Descriptive and bivariate analyses were performed with survey, blood-lead, and environmental data. Multivariate logistic regression techniques were used to determine risk factors for childhood mortality. Results: We surveyed 119 family compounds. One hundred eighteen of 463 (25%) children aged <5 years had died in the last year. We tested 59% (204/345) of children, aged <5 years, and all were lead poisoned (≥10 µg/dL); 97% (198/204) of children had blood-lead levels ≥45 µg/dL, the threshold for initiating chelation therapy. Gold ore was processed inside two-thirds of the family compounds surveyed. In multivariate modeling significant risk factors for death in the previous year from suspected lead poisoning included: the child's age, the mother performing ore-processing activities, community well as primary water source, and the soil-lead concentration in the compound. Conclusion: The high levels of environmental contamination, percentage of children aged <5 years with elevated blood-lead levels (97%, >45 µg/dL), and incidence of convulsions among children prior to death (82%) suggest that most of the recent childhood deaths in the two surveyed villages were caused by acute lead poisoning from gold ore-processing activities. Control measures included environmental remediation, chelation therapy, public health education, and control of mining activities

Publisher: National Institute of Environmental Health Sciences
Year: 2011
DOI identifier: 10.1289/ehp.1103965
OAI identifier: oai:fieldresearch.msf.org:10144/220352
Provided by: MSF Field Research
Journal:

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Citations

  1. (2006). Acute lead poisoning associated with backyard lead smelting in Jamaica.
  2. (1999). Agency for Toxic Substances and Disease Registry.
  3. (2011). Available: http://www.unhcr.org/472af2972.pdf [accessed 6
  4. (1972). Biologic effects of lead in man. In: Lead: Airborne lead in perspective.
  5. (2006). Death of a child after ingestion of a metallic charm—Minnesota.
  6. (2008). Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects. Available:
  7. (2010). Enviromental and occupational exposures to mercury among indigenous people in Dunkwa-On-Offin, a small scale gold mining area in the south-west of Ghana.
  8. (2006). Environmental and Health Assessment Final Report
  9. (1991). Environmental Protection Agency
  10. (2007). Environmental Protection Agency.
  11. (1999). Follow-up screening of lead-poisoned children near an auto battery recycling plant, Haina, Dominican Republic. Environ Health Perspect
  12. (2010). Fourth National Report on Human Exposures to Environmental Chemicals. Atlanta GA:
  13. (2008). Global approach to reducing lead exposure and poisoning.
  14. (2007). Global impacts of mercury supply and demand in small-scale gold mining: Report to the UNEP Governing Council Meeting Nairobi
  15. (2011). Gold mining in the peruvian Amazon: global prices, deforestation, and mercury imports.
  16. (2011). gpoaccess.gov/cgi/t/text/text-idx? [accessed 6
  17. (2007). High Commissioner for Refugees.
  18. (1942). Incidence of lead poisoning in the city of Baltimore,
  19. (2003). Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter.
  20. (2003). International environmental health for the pediatrician: case study of lead poisoning. Pediatrics 112(1):259-264. Page 23 of 31 Freeney
  21. Jones RL.2010 Comparisons between ICP-DRC-MS and ICPCCT-MS for the analysis of Manganese in whole human blood. In:
  22. (2009). Lead poisoning among internally displaced Roma, Ashkali and Egyptian children in the United Nations-Administered Province of Kosovo.
  23. (2006). Lead. In: Goldfrank’s Toxicologic Emergencies.
  24. (2006). Longitudinal associations between blood lead concentrations lower than 10 microg/dL and neurobehavioral development in environmentally exposed children in Mexico City.
  25. (1998). Low-lead exposure and behavior in early childhood.
  26. (2005). Low-level environmental lead exposure and children’s intellectual function: an international pooled analysis. Environ Health Perspect 113(7):894-899.
  27. (2002). Managing elevated blood lead levels among young children: recommendations from the Advisory Committee on Childhood Lead Poisoning Prevention.
  28. (2009). Mass lead intoxication from informal used lead-acid battery recycling in Dakar, Senegal. Environ Health Perspect
  29. (2010). Preventing disease through healthy environments. Available: http://www.who.int/ipcs/features/10chemicals_en.pdf [accessed 6
  30. (2009). Total blood mercury concentrations in the U.S. population: 1999-2006.
  31. (1999). Trace elements. In: Tietz textbook of clinical chemistry.
  32. (2007). Trends in blood lead levels and blood lead testing among US children aged 1 to 5 years,

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