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THE RESTORATIVE COSMETIC CONSTITUENTS OF <i>Fragraea fragrans</i> FRUITS

By Dasril Basir and Julinar Julinar

Abstract

This paper describes 3-hydroxyurs-12-en-28-oic acid and its structural isomer 3-hydroxyolean-12-en-28-oic acid isolated from Fragraea fragrans fruits and their biological activities; anti-tumor, anti-inflammation, anti-microbial, and anti-fungal included their ultra violet photo-protective effect after exposed under sunlight radiation. They are useful for cosmetic ingredient. The above triterpenes are very promoting compounds for leukemia L1210 anti-tumor due to limited reports dealing with this type triterpenoid anti-tumor test. They significantly gave IC50 value of 5.78 µg/mL against leukemia L1210 cells, relatively closed to IC50 value of drugs, 4.0 µg/mL [12-13,17]

Topics: Isomeric, ursolic acid, oleanolic acid, Fragraea fragrans, cosmetic, Chemistry, QD1-999
Publisher: Universitas Gadjah Mada
Year: 2012
DOI identifier: 10.22146/ijc.21376
OAI identifier: oai:doaj.org/article:cee928db65d2400b92895de6752af4fc
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