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Foxp3 expression is associated with aggressiveness in differentiated thyroid carcinomas

By Lucas Leite Cunha, Elaine Cristina Morari, Suely Nonogaki, Fernando Augusto Soares, José Vassallo and Laura Sterian Ward
Topics: Clinical Science
Publisher: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
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Provided by: PubMed Central
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    2. Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor.
    3. Clinical significance of measurements of antithyroid antibodies in the diagnosis of Hashimoto’s thyroiditis: comparison with histological findings.
    4. Control of regulatory T cell development by the transcription factor
    5. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
    6. Forkhead-box transcription factors and their role in the immune system. Nat Rev Immunol.
    7. FOXP3 expression and overall survival in breast cancer.
    8. Foxp3 expression in human cancer cells.
    9. FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene.
    10. Foxp3: a critical regulator of the development and function of regulatory T cells. Microbes Infect.
    11. Higher intratumoral infiltrated Foxp3+ Treg numbers and Foxp3+/CD8+ ratio are associated with adverse prognosis in resectable gastric cancer.
    12. (2008). Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: which variable determines survival of cervical cancer patients? Clin Cancer Res.
    13. Infiltration of differentiated thyroid carcinoma by proliferating lymphocytes is associated with improved disease-free survival for children and young adults.
    14. Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection.
    15. Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer.
    16. (1940). Long-term outcome in 215 children and adolescents with papillary thyroid cancer treated during
    17. (2007). Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol Immunother.
    18. Papillary thyroid carcinomas from young adults and children contain a mixture of lymphocytes.
    19. Presence of Foxp3 expression in tumor cells predicts better survival in HER2-overexpressing breast cancer patients treated with neoadjuvant chemotherapy. Breast Cancer Res Treat.
    20. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.
    21. (2009). Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. Cancer Cell.
    22. (2004). Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med.
    23. (1995). The correlation between papillary thyroid carcinoma and
    24. The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis.
    25. The regulatory T cell gene FOXP3 and genetic susceptibility to thyroid autoimmunity: an association analysis in Caucasian and Japanese cohorts.
    26. (2006). The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression. Immunol Rev.
    27. Thyroid cancer epidemiology and prognostic variables.
    28. (2007). TNM classification of thyroid carcinoma.
    29. Tumor-associated lymphocytes and increased FoxP3+ regulatory T cell frequency correlate with more aggressive papillary thyroid cancer.
    30. Tumorinfiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer.
    31. Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review.

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