Introduction: Evaluating the needs of People Living with HIV / AIDS (PLHA) and providing them with adequate care and support is important in combating the Acquired Immunodeficiency Syndrome (AIDS) epidemic. Objectives: The study was conducted to ascertain the needs of PLHA, the support obtained and required, extent of involvement in programs related to HIV and evaluate the impact of Government programs as perceived by PLHA. Methods: A cross sectional study was conducted on 150 PLHA in the districts of Indore, Neemuch and Ujjain in the state of Madhya Pradesh (India) using semi-structured interview schedules. The data was analyzed using SPSS version 12.0. Results: The major support available to the patients is the free Anti-Retroviral Therapy (ART) available at Government health care centers. The other supports obtained from self help groups and NGOs were medicines for opportunistic infections, nutritional supplements, traveling allowance to ART center for monthly doses, free monthly ration and school fees for one child in the family. The major support required were an educational plan for children, free investigations at hospitals, decentralization of ART centers and adequate employment opportunities. Involvement of PLHA in health programs was minimal: the reasons for non-involvement being unwillingness, fear of disclosure and lack of opportunity. The respondents stated that Government policies have had a positive impact and changed the perception of the society towards HIV patients. Conclusion: PLHA have a number of unmet needs and a collaborative attempt from the government and support groups is needed to meet the needs of PLHA
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