Skip to main content
Article thumbnail
Location of Repository

An Unusual Case of Gastrointestinal Bleeding

By Kristin N. Fiorino, Brian Lestini, Kim E. Nichols, Sudha A. Anupindi and Asim Maqbool


A 10-year-old boy presented with a 3-day history of worsening abdominal pain, fever, emesis and melena. Abdominal ultrasound revealed a right upper quadrant mass that was confirmed by computed tomography angiogram (CTA), which showed an 8 cm well-defined retroperitoneal vascular mass. 123Iodine metaiodobenzylguanidine (123MIBG) scan indicated uptake only in the abdominal mass. Subsequent biopsy revealed a paraganglioma that was treated with chemotherapy. This case represents an unusual presentation of a paraganglioma associated with gastrointestinal (GI) bleeding and highlights the utility of CTA and 123MIBG in evaluation and treatment

Topics: Case Report
Publisher: Hindawi Publishing Corporation
OAI identifier:
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles


    1. (2008). Abdominal paraganglioma in a pediatric patient,” Pediatric Radiology,
    2. (2006). Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes,”
    3. (2007). Clinical presentations, biochemical phenotypes, and genotypephenotype correlations in patients with succinate dehydrogenase subunit B-associated pheochromocytomas and paragangliomas,”JournalofClinicalEndocrinologyandMetabolism,
    4. (2009). e ,D .M a k e y ,T .F o j oe ta l . ,“ S u c c e s s f u lc h e m o t h e r a p yo f hepatic metastases in a case of succinate dehydrogenase subunit B-related paraganglioma.,” Endocrine,v o l .3 6 ,n o .2 ,p p .
    5. (2007). Extra-adrenal pheochromocytoma:diagnosisandmanagement,”Current Urology Reports,
    6. (2007). Gangliocytic paraganglioma: case report and review of the literature,”
    7. (2002). Germline mutations in nonsyndromic pheochromocytoma,”
    8. (2007). H.J.L.M.Timmers,A.Kozupa,C.C.Chenetal.,“Superiority of fluorodeoxyglucose positron emission tomography to other functional imaging techniques in the evaluation of metastatic SDHB-associated pheochromocytoma and paraganglioma,”
    9. (2008). i m m e r s ,K .P a c a k ,T .T .H u y n he ta l . ,“ B i o -chemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene,”
    10. (2009). Matthay et al., “Phase II study of high-dose[131I]metaiodobenzylguanidinetherapyforpatients with metastatic pheochromocytoma and paraganglioma,”
    11. (2011). Metastatic pheochromocytoma/paraganglioma related to primary tumor development in childhood or adolescence: significant link to SDHB mutations,”Journal of Clinical Oncology,
    12. (2011). Molecular cytogenetic characterization in four pediatric pheochromocytomas and paragangliomas,”
    13. (2003). Neurogenic tumors in the abdomen: tumor types and imaging characteristics,” Radiographics,v o l .2 3 ,n o .1 ,p p .
    14. (2004). Pe ¸czkowska et al., “Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD and gene mutations,”
    15. (2009). Rationale and evidence for sunitinib in the treatment of malignant paraganglioma/pheochromocytoma,”JournalofClinicalEndocrinology and Metabolism,
    16. (2007). Succinate dehydrogenase B gene mutations predict survival in patients with malignant pheochromocytomas or paragangliomas,”
    17. (2008). U.Srirangalingam,L.Walker,B.Khooetal.,“Clinicalmanifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B (SDH-B) gene mutation carriers,”
    18. (2010). W a g u e s p a c k ,T .R i c h ,E .G r u b b se ta l . ,“ Ac u r r e n tr e -view of the etiology, diagnosis, and treatment of pediatric pheochromocytoma and paraganglioma,”

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.