Location of Repository

EMMPRIN/CD147 up-regulates urokinase-type plasminogen activator: implications in oral tumor progression

By Géraldine Lescaille, Suzanne Menashi, Bénédicte Cavelier-Balloy, Farah Khayati, Cathy Quemener, Marie Pierre Podgorniak, Benyoussef Naïmi, Fabien Calvo, Céleste Lebbe and Samia Mourah
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:3342905
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles



    1. (2006). A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma. Cancer Res
    2. (2010). A: Head and neck squamous cell carcinoma: new translational therapies.
    3. (2008). Atakilit A, Ramos DM: EMMPRIN modulates migration and deposition of TN-C in oral squamous carcinoma. Anticancer Res
    4. (2004). Brakenhoff RH: Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus.
    5. (2006). BS: Expression of plasminogen activator inhibitor-1, urokinase receptor and laminin gamma-2 chain is an early coordinated event in incipient oral squamous cell carcinoma.
    6. (2003). CL: Expression of extracellular matrix metalloprotease inducer in laryngeal squamous cell carcinoma. Laryngoscope
    7. (2000). DM: Expression of emmprin by oral squamous cell carcinoma.
    8. (2008). EL: Modulation of tumor cell growth in vivo by extracellular matrix metalloprotease inducer. Arch Otolaryngol Head Neck Surg
    9. (2006). Emmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression. Pathol Int
    10. (2003). Emmprin (CD147), a cell surface regulator of matrix metalloproteinase production and function. Curr Top Dev Biol
    11. (2009). EMMPRIN promotes angiogenesis through hypoxia-inducible factor-2alpha-mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2. Blood
    12. (2010). EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2. PLoS One
    13. (2007). et al: Extracellular matrix metalloproteinase inducer up-regulates the urokinase-type plasminogen activator system promoting tumor cell invasion. Cancer Res
    14. (2003). et al: Identification of potential biomarkers of lymph node metastasis in oral squamous cell carcinoma by cDNA microarray analysis.
    15. (2010). et al: Urinary-type plasminogen activator receptor/alpha 3 beta 1 integrin signaling, altered gene expression, and oral tumor progression. Mol Cancer Res
    16. (2006). Increased EMMPRIN (CD 147) expression during oral carcinogenesis. Exp Mol Pathol
    17. (2005). L: Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. Cancer Res
    18. (1992). Marnock WE: DOK, a cell line established from human dysplastic oral mucosa, shows a partially transformed nonmalignant phenotype.
    19. (2005). Menashi S: EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. Biochimie
    20. (2008). Menashi S: Role of emmprin/CD147 in tissue remodeling. Connect Tissue Res
    21. (2003). Miyauchi T: Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion. Histol Histopathol
    22. (1995). Nabeshima K: The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res
    23. (2010). RG: Laminin-derived peptide AG73 regulates migration, invasion, and protease activity of human oral squamous cell carcinoma cells through syndecan-1 and beta1 integrin. Tumour Biol
    24. (2011). Rosenthal EL: Fibroblast growth factor receptor mediates fibroblastdependent growth in EMMPRIN-depleted head and neck cancer tumor cells. Mol Cancer Res
    25. (2005). S: An autocrine loop directed by the vascular endothelial growth factor promotes invasiveness of human melanoma cells.
    26. (2008). Slomiany MG: Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance. Drug Resist Updat
    27. (2007). Stack MS: Urinary-type plasminogen activator (uPA) and its receptor (uPAR) in squamous cell carcinoma of the oral cavity.
    28. (2005). Toole BP: Roles of the multifunctional glycoprotein, emmprin (basigin; CD147), in tumour progression. Thromb Haemost
    29. (2001). Toole BP: Tumorigenic potential of extracellular matrix metalloproteinase inducer.
    30. (2010). Vermorken JB: Advances in the systemic treatment of head and neck cancers. Curr Opin Oncol
    31. (2010). X: CD147/basigin promotes progression of malignant melanoma and other cancers.
    32. (2006). Ziober BL: The extracellular matrix in oral squamous cell carcinoma: friend or foe? Head Neck

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.