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The biopsychology of maternal behavior in nonhuman mammals

By Dr. Mark B. Kristal

Abstract

The term “maternal behavior,” when applied to nonhuman mammals, includes the behaviors exhibited in preparation for the arrival of newborn, in the care and protection of the newly arrived young, and in the weaning of those young, and represents a complex predictable pattern that is often regarded as a single, comprehensive, species-specific phenomenon. Although the delivering first-time mammalian mother is immediately and appropriately maternal, a maternal “virgin” with no prior exposure to young does not show immediate and appropriate behavior toward foster young. Nevertheless, the virgin female, and indeed the male, possess the neural circuitry that underlies the pattern referred to as maternal behavior, despite not exhibiting the pattern under normal circumstances. At parturition, or after extensive exposure to young, what emerges appears to be a single stereotyped maternal behavior pattern. However, it is actually a smoothly coordinated constellation of simpler actions with proximate causes that, when sequenced properly, have the appearance of a motivated, purposive, adaptive, pattern of caretaking. Over the past 50 years, much research has focused on finding the principal external and internal factors that convert the nonmaternal behavior patterns of the nonpregnant nullipara, the virgin, to the almost immediate and intense maternal behavior characteristic of the puerpera, the mother. This review is an attempt to summarize the many comprehensive, even encyclopedic, reviews of these factors, with an emphasis on brain mechanisms, and to highlight the gaps that remain in understanding the processes involved in the almost immediate onset of maternal caretaking behaviors observed in mammals at delivery. Where possible, the reader is directed to some of those excellent reviews

Topics: Behavioral Biology, Neuroendocrinology, Psychobiology, Physiological Psychology, Behavioral Neuroscience, Animal Behavior, Comparative Psychology, Neurochemistry
Publisher: National Research Council of the National Academies
Year: 2009
DOI identifier: 10.1093/ilar.50.1.51
OAI identifier: oai:cogprints.org:6341

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Citations

  1. (1984). A quantitative analysis of the roles of dosage, sequence, and duration of estradiol and progesterone exposure in the regulation of maternal behavior in the rat.
  2. (2002). Acute hunger of rat pups elicits increased kyphotic nursing and shorter intervals between nursing bouts: Implications for changes in nursing with time postpartum. 1
  3. (1995). An analysis of approach/withdrawal pro cesses in the initiation of maternal behavior in the laboratory rat.
  4. (2001). Animal models of social stress: Effects on behavior and brain neurochemical systems.
  5. (1971). Aspects of nonhormonal maternal behavior in the rat.
  6. (1986). Bare 1£, vom Saal FS.
  7. (1977). Bile, prolactin, and the maternal pheromone.
  8. (1983). Brain l3-endorphin during pregnancy, partu rition and the postpartum period.
  9. (1994). Brain opioids and mother-infant social motivation. Acta Prediatr Suppl
  10. (1966). Caesarean delivery and maternal behavior of primiparous and mUltiparous rats. 1
  11. (1996). Changes in pain threshold during the reproductive cycle of the female rat.
  12. (2008). Characterization of maternal motivation in the lactating rat: Contrasts between early and late postpar tum responses. Horm Behav 54:294-30 I.
  13. (2000). De Vries G1.
  14. (2007). Dopamine D 1 receptor stimulation of the nucleus accumbens or the medial preoptic area promotes the onset of maternal behavior in pregnancy-terminated rats.
  15. (1999). Dopamine receptor blockade in the nucleus accumbens inhibits maternal retrieval and licking. but enhances nursing behavior in lactating rats.
  16. (1973). Effects of lateral hypothalamic lesions on placentophagia in virgin. primiparous, and multiparous rats.
  17. (1990). Endocrine regulation of parental behavior in rodents.
  18. (1985). Endogenous opioid peptides and hypothalamic neuroen docrine neurones.
  19. (2002). Endogenous opioid regulation of stress induced oxytocin release within the hypothalamic paraventricular nucleus is reversed in late pregnancy: A microdialysis study.
  20. (1991). Enhancement of opioid-mediated analgesia: A solution to the enigma of placentophagia.
  21. (1987). Environmental temperature and maternal behavior in Rattus norvegicus.
  22. (1990). Estrogen and progesterone regulate opiate receptor densities in multiple brain regions.
  23. (1995). Estrogen modulation of oxytocin and its relation to behavior.
  24. (1996). Ferret mothers provide more anogenital licking to male offspring: Possible contribution to psychosexual differentiation.
  25. (1980). From motivation to action: Func tional interface between the limbic system and the motor system.
  26. (1972). Genital sensory field: Enlarge ment by estrogen treatment in female rats.
  27. (1994). Gonadal steroid hormones and hypothalamic opioid circuitry.
  28. (1970). Hormonal induction of ma ternal behavior in the ovariectomized nulliparous rat.
  29. (1992). Hormonal regulation of medial preoptic J.l-opioid receptor density before and after parturition.
  30. (2002). Hormones and parental behavior.
  31. (1972). Humoral factors underlying maternal behavior at parturition: Cross transfusion between freely moving rats. 1
  32. (1994). Hypothermic vocalizations of rat pups (Rattus norvegicus) elicit and direct maternal search behavior.
  33. (1987). Induction of maternal behavior in rats: Effects of pseudopregnancy termination and placenta-smeared pups.
  34. (1988). Infanticide in rats: Male strategy and female counter-strategy.
  35. (1984). Influence of amniotic fluids in the manifestation of maternal behavior in parturient ewes.
  36. (1995). Ingestion of amniotic fluid by postpartum rats enhances morphine analgesia without liability to mater nal behavior.
  37. (2009). Initiation of maternal behavior in the rat: Possible involvement of limbic norepinephrine.
  38. (1987). Intracerebroventricular oxytocin stimulates maternal behavior in the sheep.
  39. (2002). Involvement of the medial prefrontal cortex in mediating behavioral responses to odor cues rather than olfactory recognition memory.
  40. (2005). Is mom too sensitive? Impact of maternal stress during gestation.
  41. (2001). Lactogenic hormone regulation of maternal behavior.
  42. (1995). Lateral habenula neurons are necessary for the hormonal onset of maternal behavior and for the display of postpartum estrus in naturally parturient female rats.
  43. (2001). Lonstein lS.
  44. (1991). Maternal behavior of female rats with 6-0HDA lesions in the ventral striatum: Characterization of the pup retrieval deficit.
  45. (1974). Maternal behavior upon experimental and normal termination of pseudopregnancy in the rat.
  46. (2003). Maternal behavior: Activation of the central oxytocin receptor system in parturient rats?
  47. (1989). Maternal behavior: Sensory, hormonal, and neural determi nants.
  48. (1984). Maternal contributions to the development of masculine sexual behavior in laboratory rats.
  49. (2008). Maternal infanticide in sows: Incidence and behavioral comparisons between savaging and non-savaging sows at parturition.
  50. (1999). Maternal motivation of lactating rats is disrupted by low dosages of haloperidol.
  51. (1993). Modulation of hypothalamic mu-opioid receptor density by estrogen: A quantitative autoradiographic study of the female C57BL/61 mouse.
  52. (1991). Morphine and corticotrophin-releasing factor potentiate maternal acceptance in multiparous ewes after vagi nocervical stimulation.
  53. (2007). Natural varia tions in postpartum maternal care in inbred and outbred mice.
  54. (1987). Neuroanatomical boundaries of the reward-relevant opiate-receptor field in the ventral tegmental area as mapped by the conditioned place preference method in rats.
  55. (2006). Neuropeptidergic regulation of affiliative behavior and social bonding in animals.
  56. (1967). Nonhormonal basis of maternal behavior in the rat.
  57. (1983). Opiate reward mechanisms mapped by intracranial self-administration.
  58. (1985). Opioid peptides of the pituitary and hypothala mus: Changes in pregnant and lactating rats. 1
  59. (1990). opioid receptor involve ment in maternal behavior.
  60. (1996). Opioid stimulation in the ventral tegmen tal area stimulates maternal behavior in rats.
  61. (1995). Opioids and sexual behavior of male rats: Involvement of the medial preoptic area.
  62. (1994). Oxytocin activates the postpartum onset of rat maternal behavior in the ventral tegmental and medial preoptic areas.
  63. (1985). Oxytocin and mothering behavior in rats.
  64. (2006). Oxytocin receptors in the nucleus accum bens facilitate "spontaneous" maternal behavior in adult female prairie voles.
  65. (2000). Oxytocin, motherhood and bonding. Exp Physiol 85:IIIS-124S.
  66. (2001). Oxytocin: Who needs it?
  67. (1998). Participation of placental opioid-enhancing factor in opioid-modulated events at parturition.
  68. (2007). Parturient behavior in farmed mink (Mustela vison) in relation to early kit mortality.
  69. (2006). Parturition in the rat: A physiological pain model.
  70. (2007). Paternal care in rodents: Weaken ing support for hormonal regulation of the transition to behavioral fatherhood in rodent animal models of biparental care.
  71. (2007). Periaqueductal gray cholecystokinin infusions block morphine-induced disruption of maternal behavior.
  72. (1976). Placentophagia in nonpregnant rats: Influ ence of estrous cycle stage and birthplace.
  73. (1980). Placentophagia: A biobehavioral enigma (or De gustibus non disputandum est).
  74. (1984). Plasma b-endorphin concentrations prior to and during pregnancy, in labor, and after delivery.
  75. (1987). Preoptic area opioids and opiate receptors increase during pregnancy and decrease during lactation.
  76. (2006). Reproductive experience differentially affects spatial reference and working memory perfor mance in the mother.
  77. (1987). Sensory innervation of the external and internal genitalia of the female rat.
  78. (2002). Sensory, hormonal, and neural control of maternal aggression in laboratory rodents.
  79. (1956). Sources of order in the maternal behavior of animals.
  80. (2006). Stress during gestation alters postpar tum maternal care and the development of the offspring in a rodent model.
  81. (1969). The Behavior of Domestic Animals.
  82. (1987). The importance of amniotic fluids for the establishment of maternal behavior in experienced and inexperienced ewes.
  83. (1937). The neural basis of innate behavior. I. Effects of cortical lesions upon the maternal behavior pattern in the rat.
  84. (1938). The neural basis of innate behavior. II. Relative effects of partial decortications in adulthood and infancy upon the maternal behavior of the primiparous rat.
  85. (2003). The nucleus accumbens shell is critical for normal expression of pup-retrieval in postpartum female rats.
  86. (1998). The role of vocaliza tions in the behavioral regulation of reproductive behavior in rodents.
  87. (1983). The suppression of infanticide in mother rats.
  88. (1986). Thermal control of mother-young contact in Norway rats: Factors mediating the chronic elevation of maternal temperature.
  89. (2002). Thermal control of mother-young contact revisited: Hyperthermic rats nurse normally.
  90. (1983). Vaginal stimulation: An important determinant in maternal bonding in sheep.
  91. (2004). Variations in nucleus accumbens dopamine associated with individual differences in maternal behavior in the rat.

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