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The Role of the N-Domain in the ATPase Activity of the Mammalian AAA ATPase p97/VCP*

By Hajime Niwa, Caroline A. Ewens, Chun Tsang, Heidi O. Yeung, Xiaodong Zhang and Paul S. Freemont

Abstract

Background: p97/VCP disease-linked mutations increase ATPase activity and destabilize the N-D1 domain interaction

Topics: Molecular Bases of Disease
Publisher: American Society for Biochemistry and Molecular Biology
OAI identifier: oai:pubmedcentral.nih.gov:3318706
Provided by: PubMed Central
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