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Use of thrombolytic therapy in cerebral venous sinus thrombosis with ulcerative colitis

By Kavitha Kothur, Subhash Kaul, S. Rammurthi, V. C. S. Srinivasarao Bandaru, Suvarna Alladi T. Suryaprabha and K. Rukmini Mrudula


Cerebral venous thrombosis developing concurrently with active ulcerative colitis poses a therapeutic dilemma. We report the case of a 31-year-old woman who developed dural venous sinus thrombosis during the course of active ulcerative colitis in whom we accomplished clot lysis using intrasinus urokinase. The success of the procedure was assessed by improvement in the patient's neurological condition and resolution of imaging features without any bleeding complications. We also reviewed literature on various modalities of treatment of sinus venous thrombosis in patients with ulcerative colitis and outcome

Topics: Case Report
Publisher: Medknow Publications & Media Pvt Ltd
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Provided by: PubMed Central
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