Article thumbnail

Pandemic (H1N1) 2009 Virus and Down Syndrome Patients

By Rogelio Pérez-Padilla, Rosario Fernández, Cecilia García-Sancho, Francisco Franco-Marina, Octavio Aburto, Hugo López-Gatell and Ietza Bojórquez


We compared prevalence of hospitalization, endotracheal intubation, and death among case-patients with and without Down syndrome during pandemic (H1N1) 2009 in Mexico. Likelihoods of hospitalization, intubation, and death were 16-fold, 8-fold, and 335-fold greater, respectively, for patients with Down syndrome. Vaccination and early antiviral drug treatment are recommended during such epidemics

Topics: Dispatch
Publisher: Centers for Disease Control and Prevention
OAI identifier:
Provided by: PubMed Central

Suggested articles


  1. (1992). Abnormal serum IgG subclass pattern in children with Down’s syndrome. Arch Dis Child.
  2. Adults with Down’s syndrome: the prevalence of complications and health care in the community.
  3. (1976). Childhood deaths in Down’s syndrome. Survival curves and causes of death from a total population study in
  4. (2009). Disease control and Prevention. Use of infl uenza a (H1N1) 2009 monovalent vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP),
  5. (2007). Down syndrome: a novel risk factor for respiratory syncytial virus bronchiolitis—a prospective birth-cohort study. Pediatrics.
  6. (1997). Increased incidence and prevalence of diabetes mellitus in Down’s syndrome. Arch Dis Child.
  7. (2010). Infl uenza A (H1N1) Virus Investigation Team, Dawood
  8. Intrinsic abnormalities of lymphocyte counts in children with Down syndrome.
  9. neonatal characteristics, and fi rst-year mortality of Down syndrome: a national study.
  10. Nonspecifi c immunity in Down syndrome: a study of chemotaxis, phagocytosis, oxidative metabolism, and cell surface marker expression of polymorphonuclear cells.
  11. Population-based study of congenital heart defects in Down syndrome.
  12. (2009). Respiratory infections, Down’s syndrome and congenital heart disease: The CIVIC 21 study [in Spanish]. An Pediatr (Barc).
  13. (1985). The relationship of congenital heart disease and respiratory infection mortality in patients with Down’s syndrome. J Ment Defi c Res.

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.