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Finding Balance: T cell Regulatory Receptor Expression during Aging

By Mary M. Cavanagh, Qian Qi, Cornelia M. Weyand and Jörg J. Goronzy

Abstract

Aging is associated with a variety of changes to immune responsiveness. Reduced protection against infection, reduced responses to vaccination and increased risk of autoimmunity are all hallmarks of advanced age. Here we consider how changes in the expression of regulatory receptors on the T cell surface contribute to altered immunity during aging

Topics: Review
Publisher: JKL International LLC
OAI identifier: oai:pubmedcentral.nih.gov:3295076
Provided by: PubMed Central
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