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Neural Correlates of Dynamically Evolving Interpersonal Ties Predict Prosocial Behavior

By Johannes J. Fahrenfort, Frans van Winden, Benjamin Pelloux, Mirre Stallen and K. Richard Ridderinkhof


There is a growing interest for the determinants of human choice behavior in social settings. Upon initial contact, investment choices in social settings can be inherently risky, as the degree to which the other person will reciprocate is unknown. Nevertheless, people have been shown to exhibit prosocial behavior even in one-shot laboratory settings where all interaction has been taken away. A logical step has been to link such behavior to trait empathy-related neurobiological networks. However, as a social interaction unfolds, the degree of uncertainty with respect to the expected payoff of choice behavior may change as a function of the interaction. Here we attempt to capture this factor. We show that the interpersonal tie one develops with another person during interaction – rather than trait empathy – motivates investment in a public good that is shared with an anonymous interaction partner. We examined how individual differences in trait empathy and interpersonal ties modulate neural responses to imposed monetary sharing. After, but not before interaction in a public good game, sharing prompted activation of neural systems associated with reward (striatum), empathy (anterior insular cortex and anterior cingulate cortex) as well as altruism, and social significance [posterior superior temporal sulcus (pSTS)]. Although these activations could be linked to both empathy and interpersonal ties, only tie-related pSTS activation predicted prosocial behavior during subsequent interaction, suggesting a neural substrate for keeping track of social relevance

Topics: Neuroscience
Publisher: Frontiers Research Foundation
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Provided by: PubMed Central

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  1. (1972). A measure of emotional empathy.
  2. (1996). A new brain regionforcoordinatingspeecharticulation.
  3. (2004). A region of right posterior superior temporal sulcus responds to observed intentional actions.
  4. (2010). Activity in the amygdala elicited by unfair divisions predicts social value orientation.
  5. (2009). Activityinthesuperiortemporalsulcus highlights learning competence in an interaction game.
  6. (2007). Altruism is associated withanincreasedneuralresponseto agency.
  7. (2002). Altruistic punishment in humans.
  8. (2011). An fMRI investigation of empathy for ‘social pain’ and subsequent prosocial behavior.
  9. and Siem,B.(2006).Empathy-motivated helping: the moderating role of group membership.
  10. (2003). Both of us disgusted in My Insula: the common neural basis of seeing and feeling disgust.
  11. Brain responses to the acquired moral status of faces.
  12. (2009). Circular analysis in systems neuroscience: the dangers of double dipping.
  13. (2000). Cognitive and emotional influences in anterior cingulate cortex.
  14. (1995). Controllingthefalsediscoveryrate– a practical and powerful approach to multiple testing.
  15. (1994). Cortical control of saccades and fixation i nm a n–ap e ts t u d y
  16. (2010). Degrees of uncertainty: an overview and framework for future research on experience-based choice.
  17. Dolan,R.J.,Friston,K.J.,andFrackowiak,R.S.(2004).Temporaldifference models describe higher-order learning in humans.
  18. (2002). Dorsal anterior cingulate cortex: a role in rewardbased decision making.
  19. (2006). Empathic neural responses are modulated by the perceivedfairnessof others.Nature 439,
  20. (2000). Empathy and sympathy,”
  21. (2004). Empathy for pain involvestheaffectivebutnotsensory components of pain.
  22. (2007). Empathy for positive and negative emotions in the gustatory cortex.
  23. (1989). Frameworks of analysis for the neural representation of animate objects and actions.
  24. (2012). Frontiers in Neuroscience | Decision Neuroscience
  25. G.E.(1998).Neuralcorrelatesoflevelsof emotionalawareness:evidence of an interaction between emotion and attention in the anterior cingulate cortex.
  26. (2005). Getting to know you: reputation and trust in a two-person economic exchange.
  27. (1988). Group-size effects in public-goods provision – the voluntary contributions mechanism.
  28. (2009). How do you feel – now?Theanteriorinsulaandhuman awareness.
  29. (2006). Human fronto-mesolimbic networks guide decisionsaboutcharitabledonation.
  30. (2001). Investigating the functional anatomy of empathy and forgiveness.
  31. (2000). Movement and mind: a functional imaging study of perception and interpretation of complex intentional movement patterns.
  32. (2010). Neural basis of extraordinary empathy and altruistic motivation.
  33. (2012). Neural correlates of dynamically evolving interpersonal ties predict prosocial behavior.
  34. (2008). Neural correlates of mentalizing-related computations during strategic interactions in humans.
  35. (2010). Neural responses to ingroup and outgroup members’ suffering predict individual differences in costly helping.
  36. (2004). Neural systems supporting interoceptive awareness.
  37. (1994). Neurophysiology and cognitive functions of the striatum.
  38. (2008). On the nature, modeling, and neural bases of social ties.
  39. (2011). paper pending published: 17
  40. (2006). Perceiving identical sounds as speech or non-speech modulates activity in the left posterior superiortemporalsulcus.Neuroimage 30,
  41. (1995). Public goods: a survey of experimental research,”
  42. (2008). Putting the altruismbackintoaltruism:theevolution of empathy. A n n u .R e v .P s y -chol.
  43. (1997). Relations among personality scales of aggression,violence,andempathy:validationalevidence bearing on the risk of eruptiveviolencescale.Aggress.Behav.23,
  44. (2002). Social ties in a public good experiment.
  45. (1996). Specific involvement of human parietal systems and the amygdala in the perception of biological motion.
  46. (2004). Superior temporal sulcus anatomical abnormalities in childhood autism: a voxel-based morphometry MRI study.
  47. (1991). The Altruism Question:TowardaSocialPsychologicalAnswer.Hillsdale,NJ:L.Erlbaum.
  48. (1992). The anatomy of phonological and semantic processing in normal subjects.
  49. (2004). The contribution of the insula to motoraspectsof speechproduction: a review and a hypothesis.
  50. (1984). The effect of social motives, communication and group-size on behavior in an N-person multi-stage mixed-motive game.
  51. (2004). The neural bases of cooperation and competition: an fMRI investigation.
  52. (2012). The neural correlate of interpersonal ties C.D.(2002).Aneuralbasisforsocial cooperation.
  53. (1999). The pursuit of joint outcomes and equality in outcomes: an integrative model of social value orientation.
  54. (2010). The reward circuit: linking primate anatomy and human imaging.
  55. (2012). This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits noncommercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.
  56. (2009). What do i care? Perceived ingroup responsibility and dehumanization as predictors of empathy felt for the victim group. Group Process. Intergroup Relat.
  57. (2010). When giving is good: ventromedial prefrontal cortex activation for others’intentions.

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