Article thumbnail

A-6G and A-20C Polymorphisms in the Angiotensinogen Promoter and Hypertension Risk in Chinese: A Meta-Analysis

By Wei Gu, Jielin Liu, Qiuli Niu, Hao Wang, Yuqing Lou, Kuo Liu, Lijuan Wang, Zuoguang Wang, Jingmei Zhang and Shaojun Wen
Topics: Research Article
Publisher: Public Library of Science
OAI identifier:
Provided by: PubMed Central

Suggested articles


  1. (1998). 6A promoter variant of angiotensinogen and blood pressure variation in Canadian Oji-Cree.
  2. (1998). A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro.
  3. (2001). A-6G variant of the angiotensinogen gene and essential hypertension in Han, Tibetan, and Yi populations.
  4. (2001). Angiotensinogen gene core promoter variants and non-modulating hypertension.
  5. (2003). Angiotensinogen gene haplotype and hypertension: interaction With ACE gene I allele.
  6. (1999). Angiotensinogen gene polymorphism near transcription start site and blood pressure: role of a T-to-C transition at intron I.
  7. (2006). Angiotensinogen promoter sequence variants in essential hypertension.
  8. (2000). Association analysis of variants in the core promoter region of angiotensinogen gene with essential hypertension in Tibetan population.
  9. (2002). Association between molecular variants of the angiotensinogen gene and hypertension in Amis tribes of eastern Taiwan.
  10. (2009). Association between renin–angiotensin system gene polymorphism and essential hypertension: a community-based study.
  11. (2010). Association between the A-6G variant in 59 upstream core promoter of angiotension gene and essential hypertension in Bai population.
  12. (2011). Association of a-adducin and G-protein b3 genetic polymorphisms with hypertension: a meta-analysis of Chinese populations.
  13. (2010). Association of angiotensinogen gene M235T and angiotensin-converting enzyme gene I/D polymorphisms with essential hypertension in Han Chinese population: a metaanalysis.
  14. (2010). Association of the renin gene polymorphism, three angiotensinogen gene polymorphisms and the haplotypes with essential hypertension in the Mongolian population.
  15. (2002). Association studies of angiotensinogen gene and cardiocerebrovascular disease. Shanghai: Shang Hai Di Er Yi Ke Da Xue. 51 p. [Article in Chinese].
  16. (2006). Associations between RAS gene polymorphisms, environmental factors and hypertension in Mongolian people.
  17. (1997). Bias in meta-analysis detected by a simple, graphical test.
  18. (2007). Correlation between angiotensinogen gene and primary hypertension with cerebral infarction in the Li nationality of China.
  19. (2008). Correlation between angiotensinogen gene polymorphisms and essential hypertension in Chinese population.
  20. (2003). Four polymorphisms of renin-angiotensin system in essential hypertension in a kazakh genetic isolate.
  21. (1999). Gene polymorphism of the renin-angiotensin system in essential hypertension.
  22. (2006). Genetic basis of hypertension: revisiting angiotensinogen.
  23. (2006). Genetic gene polymorphisms and interactions of hypertension in Mongolian people. Zhongguo Gong Gong Wei Sheng 22: 1332–1333. [Article in Chinese].
  24. (2007). Genetic polymorphisms of angiotensinogen and essential hypertension in a Tibetan population.
  25. (1993). Genetics of essential hypertension.
  26. (2005). Genotyping the –6A/ G functional polymorphism in the core promoter region of angiotensinogen gene by microchip electrophoresis.
  27. (2009). Haplotype-based association of the renin-angiotensin-aldosterone system genes polymorphisms with essential hypertension among Han Chinese: the Fangshan study.
  28. (1999). Kumar A
  29. (2003). Measuring inconsistency in meta-analyses.
  30. (2004). Meta-analysis of genetic association studies.
  31. (2008). MetaAnalysis of the association of 4 angiotensinogen polymorphisms with essential hypertension: a role beyond M235T?
  32. (1995). Misleading meta-analysis.
  33. (1992). Molecular basis of human hypertension: role of angiotensinogen.
  34. (1955). On estimating the relation between blood group and disease.
  35. (1991). Publication bias in clinical research.
  36. (1997). Quantitative synthesis in systematic reviews.
  37. (2004). Relationship between six single nucleotide polymorphisms of angiotensinogen gene and essential hypertension.
  38. (2007). Relationship between the mononucleotide polymorphism of angiotensinogen gene at 59 end promoter A-20C and A-6G and essential hypertension in Mongol nationality. Zhongguo Zu Zhi Gong Cheng Yang Jiu Yu Lin Chuang Kang Fu 11: 5865–5868. [Article in Chinese].
  39. (1995). Renin–angiotensin system gene polymorphisms in essential hypertension in Tibetan population. .Beijing: Zhong Guo Xie He Yi Ke Da Xue. 175 p. [Article in Chinese].
  40. (2003). Renin–angiotensin–aldosterone system: fundamental aspects and clinical implications in renal and cardiovascular disorders.
  41. (2005). Report on cardiovascular disease in China. Beijing: Encyclopedia of China Publishing House.
  42. (2008). Study on the association of predisposing genes with essential hypertension among Kazakhs ethnic group in Xinjiang. Zhonghua Liu Xing bing Xue Za Zhi 29: 752–756. [Article in Chinese].
  43. (1998). The Chinese human genome diversity project.
  44. (2001). The genetics of essential hypertension.
  45. (2002). The relationship between haplotypes of angiotensinogen gene and essential hypertension.
  46. (2004). The relationship between the variants in 59 upstream core promoter A(-6)G and A(-20)C of angiotension gene and essential hypertension in Kazakans of Xinjiang.
  47. (2008). The study of associations between single nucleotide polymorphisms of angiotension gene and renin gene and cerebralinfarction.
  48. (2004). Three singlenucleotide polymorphisms of the angiotensinogen gene and susceptibility to hypertension: single locus genotype vs. haplotype analysis.
  49. (2010). Transgenic mice with -6A haplotype of the human angiotensinogen gene have increased blood pressure compared with -6G haplotype.
  50. (1990). Underreporting research is scientific misconduct.

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.