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Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptake

By Xiuying Li, Dan Chen, Chaoyi Le, Chunliu Zhu, Yong Gan, Lars Hovgaard and Mingshi Yang
Topics: Original Research
Publisher: Dove Medical Press
OAI identifier: oai:pubmedcentral.nih.gov:3235033
Provided by: PubMed Central

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Citations

  1. (2006). A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats. Mol Cancer Ther.
  2. Barrier properties of gastrointestinal mucus to nanoparticle transport.
  3. Binding and uptake of biodegradable poly-DL-lactide micro- and nanoparticles in intestinal epithelia.
  4. (2010). Biodegradable nanoparticles composed entirely of safe materials that rapidly penetrate human mucus. Angew Chem Int Ed Engl.
  5. Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery.
  6. Chitosan/alginate nanoparticles stabilized by Poloxamer for the controlled release of 5-fluorouracil.
  7. (2009). Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus. Mol Pharm.
  8. Cystic fibrosis sputum: a barrier to the transport of nanospheres.
  9. Different internalization pathways of polymeric micelles and unimers and their effects on vesicular transport.
  10. Direct observation of Poloxamer 188 insertion into lipid monolayers.
  11. Effect of size, surface charge, and hydrophobicity on the translocation of polystyrene microspheres through gastrointestinal mucin.
  12. Effect of the non-ionic surfactant Poloxamer 188 on passive permeability of poorly soluble drugs across Caco-2 cell monolayers.
  13. Enhanced oral bioavailability of cyclosporine A by liposomes containing a bile salt.
  14. Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport.
  15. Humoral immune response of carp (Cyprinus carpio) induced by oral immunization with liposomeentrapped antigen.
  16. (1994). Improvements in the preparation of liposomes for electron-microscopy and electron-spectroscopic imaging (ESI). Microsc Res Tech.
  17. In vitro and in vivo evaluation of WGA-carbopol modified liposomes as carriers for oral peptide delivery.
  18. Interaction and complexation of phospholipid vesicles and triblock copolymers.
  19. Interaction between Pluronic F127 and dioctadecyldimethylammonium bromide (DODAB) vesicles studied by differential scanning calorimetry.
  20. Interaction of poloxamers with liposomes: an isothermal titration calorimetry study.
  21. Interactions of Pluronics with phospholipid monolayers at the air-water interface.
  22. Investigating the uptake and intracellular fate of pH-sensitive liposomes by flow cytometry and spectral bio-imaging.
  23. (2011). Lipid-based oral multiparticulate formulations – advantages, technological advances and industrial applications. Expert Opin Drug Deliv.
  24. Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation.
  25. (2011). Mucus penetrating targeted nano-drug delivery system for cystic fibrosis.
  26. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues. Adv Drug Deliv Rev.
  27. (2010). Phospholipids and lipid-based formulations in oral drug delivery. Pharm Res.
  28. Physical conjugation of (tri-) block copolymers to liposomes toward the construction of sterically stabilized vesicle systems.
  29. Polymeric nanoparticles for oral delivery of drugs and vaccines: a critical evaluation of in vivo studies. Crit Rev Ther Drug Carrier Syst.
  30. Preparation and in vitro evaluation of mucoadhesion and permeation enhancement of thiolated chitosan-pHEMA core-shell nanoparticles.
  31. Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine.
  32. (2009). RNA interference of MBD1 in BxPC-3 human pancreatic cancer cells delivered by PLGA-Poloxamer nanoparticles. Cancer Biol Ther.
  33. (1998). Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract. Adv Drug Deliv Rev.
  34. (2007). Stability and physicochemical characteristics of PLGA, PLGA: poloxamer and PLGA: poloxamine blend nanoparticles – a comparative study. Colloids and Surfaces A Physicochemical and Engineering Aspects.
  35. The absorption behavior of cyclosporin A lecithin vesicles in rat intestinal tissue.
  36. The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo.
  37. (2010). The nonsteroidal anti-inflammatory drug indomethacin induces heterogeneity in lipid membranes: potential implication for its diverse biological action. PLoS One.
  38. The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.
  39. Topical and mucosal liposomes for vaccine delivery.
  40. Utilizing temperaturesensitive association of Pluronic F-127 with lipid bilayers to control liposome-cell adhesion.

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