Article thumbnail

The Effects of Physical Activity on the Epiphyseal Growth Plates: A Review of the Literature on Normal Physiology and Clinical Implications

By Timothy A. Mirtz, Judy P. Chandler and Christina M. Eyers
Topics: Review
Publisher: Elmer Press
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (1996). [Development and growth of the epiphysis].
  2. (1995). [Lesions of the growth plate caused by sports stress].
  3. Angiogenesis and bone growth.
  4. (1998). Athletic physeal injury in children and adolescents. Orthop Nurs
  5. Biomechanical strategies for articular cartilage regeneration. Ann Biomed Eng 2003;31(9):1114-1124.
  6. Bone development: interaction of molecular components and biophysical forces.
  7. Bone growth in length and width: the Yin and Yang of bone stability.
  8. (1992). Cartilaginous epiphysis and growth plate: normal and abnormal MR imaging findings.
  9. Characteristics of circulating growth hormone in women after acute heavy resistance exercise.
  10. (1995). Common skeletal injuries in young athletes. Sports Med
  11. (2005). Does calcitriol have actions independent from the vitamin D receptor in maintaining skeletal and mineral homeostasis? Curr Opin Nephrol Hypertens
  12. Effects of alcohol use and estrogen on bone.
  13. Effects of body composition, leptin, and adiponectin on bone mineral density in prepubertal girls.
  14. Endocrine regulation of the growth plate.
  15. (2003). Epiphyseal-plate fracture in an adolescent athlete. Athletic Therapy Today.
  16. Extracellular calcium and parathyroid hormone-related peptide signaling modulate the pace of growth plate chondrocyte differentiation.
  17. Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects 5
  18. (2001). From Wolff’s law to the Utah paradigm: insights about bone physiology and its clinical applications. Anat Rec
  19. (1997). Genetic effects on bone mass and turnoverrelevance to black/white differences.
  20. Growth hormone and bone health.
  21. (1990). Growth plate physiology and pathology.
  22. Growth without growth hormone.
  23. Hormonal regulation of growth plate cartilage.
  24. Injuries caused by physical agents.
  25. Injuries in young athletes.
  26. (2003). Integrins in growth plate cartilage. Pediatr Endocrinol Rev
  27. (1993). Leisure time physical activity in the young. Correlation with low-back pain, spinal mobility and trunk muscle strength in 15-year-old school children.
  28. (1998). Microcirculation of the distal humeral epiphyseal cartilage: implications for post-traumatic growth deformities.
  29. Molecular mechanisms of endochondral bone development.
  30. Novel paradigm on the effect of estrogen on bone.
  31. Orthopedic pitfalls in the ED: pediatric growth plate injuries.
  32. Osteoclastogenesis and growth plate chondrocyte differentiation: emergence of convergence.
  33. Pediatric orthopedic trauma: principles of management.
  34. (1999). Pediatric spine fractures. Orthop Clin North Am
  35. Physeal stress injury in the knee.
  36. Physeal widening in the knee due to stress injury in child athletes.
  37. Physiological responses to rock climbing in young climbers. Br J Sports Med 2007;41(12):852-861; discussion 861.
  38. Physiology and pathophysiology of the growth plate.
  39. Prevalence of adolescent injury from recreational exercise: an Australian perspective.
  40. Role of oestrogen in the regulation of bone turnover at the menarche.
  41. (1997). Skeletal injuries in the pediatric patient. Radiol Clin North Am
  42. (2003). Systemic and local regulation of the growth plate. Endocr Rev
  43. (2001). The effects of oestrogens on linear bone growth. Hum Reprod Update
  44. The normal and abnormal growth plate.
  45. The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation.
  46. Training issues in elite young athletes.
  47. Transcriptional regulators of chondrocyte hypertrophy.