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Devices for Prevention of Atrial Tachyarrhythmias

By Ignacio Fernández Lozano, Jorge Toquero, José Antonio Fernández Díaz, Bogdan Ionescu, Vanesa Moñivas, Pilar Ortiz and Beatriz Fuertes


Atrial fibrillation (AF) is the most frequent sustained cardiac arrhythmia in clinical practice and, although its importance has been underestimated even in recent years, we are now becoming aware of its clinical transcendence1,2,3. The classical treatment is pharmacological, but its efficacy is limited and it does have side effects4,5. Therefore, in recent years, there has been an increasing interest in other types of non-pharmacological treatments6,7. Physiologic cardiac pacing has proven to be more effective than VVI mode pacing to prevent the occurrence of AF during the follow-up of patients who have had a permanent pacemaker implanted 8,9,10. There are currently different lines of research that use different atrial pacing techniques to prevent and treat episodes of paroxysmal atrial fibrillation11,12. Techniques of multi-site pacing in the right atrium or both atria, new atrial pacing sites, prevention algorithms for paroxysmal atrial fibrillation episodes, and even high-frequency atrial tachyarrhythmia termination algorithms have all been proposed. In this article, we will try to synthesize the grounds for and findings of the different lines of research currently being developed

Topics: Indian Pacing and Electrophysiology Journal
Publisher: Indian Pacing and Electrophysiology Group
Year: 2004
OAI identifier:

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  3. (1998). ACC/AHA Guidelines for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices. Circulation. doi
  4. (2002). AF therapy study: Preventive pacing for paroxysmal atrial fibrillation. (Abstract) Pacing Clin Electrophysiol
  5. (1995). age distribution, and gender of patients with atrial fibrillation: analysis and implications.
  6. AK: Heart failure and echocardiographic changes during long-term follow-up of patients with sick sinus syndrome randomized to single-chamber atrial or ventricular pacing.
  7. (1997). Biatrial synchronous pacing: A new approach to prevent arrhythmias in patients with atrial conduction block.
  8. (1999). CD: Atrial pacing periablation for prevention of paroxysmal atrial fibrillation. Circulation doi
  9. Connolly SJ: Relationship Between Pacemaker Dependency and the Effect of Pacing Mode on Cardiovascular Outcomes.
  10. DH: Atrial septal pacing in the prevention of paroxysmal atrial fibrillation refractory to antiarrhythmic drugs.
  11. DM: Effects of physiologic pacing versus ventricular pacing on the risk of stroke and death due to cardiovascular causes. Canadian Trial of Physiologic Pacing Investigators.
  12. (2004). Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator:
  13. (1990). Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion: a metaanalysis of randomized controlled trials Circulation
  14. Efficacy of Pacing Therapies for Treating Atrial Tachyarrhythmias in Patients With Ventricular Arrhythmias Receiving a Dual-Chamber Implantable Cardioverter Defibrillator. doi
  15. Epidemiologic features of chronic atrial fibrillation: the Framingham Study.
  16. for Mode Selection Trial in Sinus-Node Function: Ventricular pacing or dual-chamber pacing for sinus-node dysfunction.
  17. (2000). for the MOST Investigators. The mode selection trial (MOST) in sinus node dysfunction: Design, rationale, and baseline characteristics of the first 1000 patients. Am Heart J
  18. Gensini GF: Interatrial septum pacing: A new approach to prevent recurrent atrial fibrillation.
  19. Hettrick D: Combined Efficacy of Atrial Septal Lead Placement and Atrial Pacing Algorithms for Prevention of Paroxysmal Atrial Tachyarrhythmia.
  20. (1998). Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation
  21. (1998). Influence of pacing modalities on the incidence of atrial fibrillation in patients without prior atrial fibrillation. A prospective study.
  22. Iturralde P: Interatrial conduction block and retrograde activation of the left atrium in paroxysmal supraventricular tachyarrhythmia. doi
  23. JC: Longterm effects of biatrial synchronous pacing to prevent drug-refractory atrial tachyarrhythmia: A nine-year experience. doi
  24. (1998). L: Quality of life and clinical outcomes in elderly patients treated with ventricular pacing as compared to with dualchamber pacing. Pacemaker Selection in the Elderly Investigators.
  25. (2003). Late Breaking Clinical Trials oral presentation at the American College of Cardiology,
  26. (2002). Left atrial and biatrial pacing. doi
  27. (2004). Long-term follow-up of patients from a randomized trial of atrial versus ventricular pacing for Indian Pacing and
  28. Mehra R: Improved suppression of recurrent atrial fibrillation with dual-site right atrial pacing and antiarrhythmic drug therapy. doi
  29. (2004). Pacing algorithms for prevention of atrial tachyarrhythmias. In Israel Indian Pacing and Electrophysiology
  30. Paroxysmal atrial fibrillation prevention by pacing in patients with pacemaker indication.
  31. (1994). PE: Prospective randomized trial of atrial versus ventricular pacing in sick sinus syndrome.
  32. (2001). Preliminary results of the AF Therapy study. Presented at the Hotline Session of the XXIIII. Congress of the European Society of Cardiology,
  33. Prevention of chronic atrial fibrillation by pacing in the region of Bachmann’s bundle: Results of a multicenter randomized trial.
  34. (1992). Proarrhythmia in patients treated for atrial fibrillation or flutter.
  35. Proclemer A: Randomized crossover comparison of right atrial appendage pacing versus interatrial septum pacing for prevention of paroxysmal atrial fibrillation in patients with sinus bradycardia.
  36. (2001). Progression to chronic atrial fibrillation after pacing: the Canadian trial of physiologic pacing. CTOPP investigators.
  37. Randomized controlled study investigating the effect of biatrial pacing in prevention of atrial fibrillation after coronary artery bypass grafting. doi
  38. Randomized, double-blind trial of simultaneous right and left atrial epicardial pacing for prevention of post-open heart surgery atrial fibrillation. doi
  39. Sun MP, Lau CP: Effects of biatrial pacing in prevention of postoperative atrial fibrillation after coronary artery bypass surgery. doi
  40. The Effect of Atrial Pacing Therapies on Atrial Tachyarrhythmia Burden and Frequency. doi
  41. (1991). The surgical treatment of atrial fibrillation. III. Development of a definitive surgical procedure.
  42. (2004). Unterberg-Buchwald et al.: Performance of a new implantable DDRP Indian Pacing and Electrophysiology
  43. (1999). Vesterlund T: Arterial thromboembolism in patients with sick sinus syndrome: Prediction from pacing mode, atrial fibrillation, and echocardiographic findings.
  44. (2004). Wyse DG: Randomized crossover comparison of DDDR versus VDD pacing after atrioventricular junction ablation for prevention of atrial fibrillation. doi

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