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Direct Fluorescent-Antibody Testing Followed by Culture for Diagnosis of 2009 H1N1 Influenza A▿

By Paul Bakerman, Lilanthi Balasuriya, Ora Fried, David Tellez, Pamela Garcia-Filion and Heidi Dalton

Abstract

During the 2009 H1N1 influenza A outbreak, 773 children were tested for influenza by direct fluorescent-antibody testing with PCR confirmation. Direct fluorescent-antibody testing has a specificity of 99.6% but a sensitivity of only 65.0%. Physicians should recognize diagnostic limitations of direct fluorescent-antibody testing, which missed one-third of infected individuals

Topics: Virology
Publisher: American Society for Microbiology
OAI identifier: oai:pubmedcentral.nih.gov:3187325
Provided by: PubMed Central
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