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Treatment of gram-positive deep sternal wound infections in cardiac surgery -experiences with daptomycin-

By Aron F Popov, Jan D Schmitto, Ahmad F Jebran, Christian Bireta, Martin Friedrich, Direndra Rajaruthnam, Kasim O Coskun, Anselm Braeuer, Jose Hinz, Theodor Tirilomis and Friedrich A Schoendube


The reported incidence of deep sternal wound infection (DSWI) after cardiac surgery is 0.4-5% with Staphylococcus aureus being the most common pathogen isolated from infected wound sternotomies and bacteraemic blood cultures. This infection is associated with a higher morbidity and mortality than other known aetiologies. Little is reported about the optimal antibiotic management. The aim of the study is to quantify the application of daptomycin treatment of DSWI due to gram-positive organisms post cardiac surgery

Topics: Research Article
Publisher: BioMed Central
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Provided by: PubMed Central

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