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E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKCζ

By Mingjin Yang, Chen Wang, Xuhui Zhu, Songqing Tang, Liyun Shi, Xuetao Cao and Taoyong Chen

Abstract

In mouse macrophages and dendritic cells, the CHIP E3 ubiquitin ligase is needed for transduction of signals initiated by TLR4 and TLR9 stimulation

Topics: Article
Publisher: The Rockefeller University Press
OAI identifier: oai:pubmedcentral.nih.gov:3182058
Provided by: PubMed Central

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