(2000). Insulin action and insulin resistance in human skeletal muscle. Diabetologia
(2005). Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer’s disease. Neuroscience
(1991). JW: Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts. Diabetes
(1983). Kashiwagi S: Iatrogenic, insulindependent, local amyloidosis. Lab Invest
(1992). Lansbury PT Jr: Amyloid fibril formation requires a chemically discriminating nucleation event: studies of an amyloidogenic sequence from the bacterial protein OsmB. Biochemistry
(2006). Lansbury PT Jr: Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins? Q Rev Biophys
(1993). Lansbury PT Jr: Seeding “one-dimensional crystallization” of amyloid: a pathogenic mechanism in Alzheimer’s disease and scrapie? Cell
(2003). Lansbury PT: Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu Rev Neurosci
(2009). Mass spectrometry characterization of the glycation sites of bovine insulin by tandem mass spectrometry.
(1993). Mechanism for the formation of methylglyoxal from triosephosphates. Biochem Soc Trans
(1972). Mercola DA: Three-dimensional atomic structure of insulin and its relationship to activity. Diabetes
(2009). Molecular basis for insulin fibril assembly.
(2007). Morozova-Roche LA: Immune reactivity towards insulin, its amyloid and protein S100B in blood sera of Parkinson’s disease patients.
(1999). Nagaraj RH: Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes. Arch Biochem Biophys
(2006). Nawroth PP: RAGE in inflammation: a new therapeutic target? Curr Opin Investig Drugs
(1988). NM: The structure of 2Zn pig insulin crystals at 1.5 A resolution. Philos Trans R Soc Lond B Biol Sci
(2006). PH: Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis.
(1988). PJ: Insulin as an amyloid-fibril protein at sites of repeated insulin injections in a diabetic patient. Diabetologia
(2008). Ponces Freire A, Cordeiro C: Protein glycation in vivo: functional and structural effects on yeast enolase.
(2005). Ponces Freire A: Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy.
(2001). Probing the mechanism of insulin fibril formation with insulin mutants. Biochemistry
(1999). Quon MJ: Insulin signalling: metabolic pathways and mechanisms for specificity. Cell Signal
(2010). Ribosylation rapidly induces alphasynuclein to form highly cytotoxic molten globules of advanced glycation end products. PLoS One
(2004). Role for glyoxalase I in Alzheimer’s disease. Proc Natl Acad Sci USA
(2002). Saibil HR: The protofilament structure of insulin amyloid fibrils.
(1988). Santoro MM: Unfolding free energy changes determined by the linear extrapolation method. 2. Incorporation of delta G degrees N-U values in a thermodynamic cycle. Biochemistry
(2005). Sipe JD: Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis. Amyloid
(2009). SM: Cellular prion protein mediates impairment of synaptic plasticity by amyloidbeta oligomers. Nature
(2006). Structural and functional changes in human insulin induced by methylglyoxal.
(1979). Studies and critique of Amido Black 10B, Coomassie Blue R, and Fast Green FCF as stains for proteins after polyacrylamide gel electrophoresis. Analytical biochemistry
(2007). Svergun DI: A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils. PLoS Biol
(1989). Takeda T: Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1. Analytical biochemistry
(1990). Takeda T: Fluorometric examination of tissue amyloid fibrils in murine senile amyloidosis: use of the fluorescent indicator, thioflavine T. Lab Invest
(2002). Tekoppel JM: Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis. Arthritis Rheum
(2009). The modification of alpha-synuclein by dicarbonyl compounds inhibits its fibril-forming process. Biochim Biophys Acta
(1994). Thornalley PJ: Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin.
(2005). Thornalley PJ: Peptide mapping of human serum albumin modified minimally by methylglyoxal in vitro and in vivo.
(2000). Transition metal-mediated glycoxidation accelerates cross-linking of beta-amyloid peptide.
(1988). Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants. Biochemistry
(2008). Uversky VN: Guiding protein aggregation with macromolecular crowding. Biochemistry