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Modulating Pharmacokinetics, Tumor Uptake and Biodistribution by Engineered Nanoparticles

By Rochelle R. Arvizo, Oscar R. Miranda, Daniel F. Moyano, Chad A. Walden, Karuna Giri, Resham Bhattacharya, J. David Robertson, Vincent M. Rotello, Joel M. Reid and Priyabrata Mukherjee
Topics: Research Article
Publisher: Public Library of Science
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Provided by: PubMed Central

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  30. (2009). Sensing of proteins in human serum using conjugates of nanoparticles and green fluorescent protein. Nature Chem(1):
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  32. (2009). siRNA delivery systems for cancer treatment. Adv Drug Deliver Rev;61):
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  36. (1994). Synthesis of Thiol-derivatised Gold Nanoparticles in a Two-phase Liquid-Liquid System. J Chem Soc Chem Commun.
  37. Tannock IF (2002) Tumor physiology and resistance to chemotherapy: repopulation and drug penetration.
  38. (2005). Targeted Delivery of Amphotericin B to Cells by Using Functionalized Carbon Nanotubes.
  39. (2011). The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliver Rev(63):
  40. (2002). Thioalkylated tetraethylene glycol: a new ligand for water soluble monolayer protected gold clusters. Chem Commun.
  41. (1990). Vascular and interstitial barriers to delivery of therapeutic agents in tumors.