Cellular prion protein protects from inflammatory and neuropathic pain

Abstract

Cellular prion protein (PrPC) inhibits N-Methyl-D-Aspartate (NMDA) receptors. Since NMDA receptors play an important role in the transmission of pain signals in the dorsal horn of spinal cord, we thus wanted to determine if PrPC null mice show a reduced threshold for various pain behaviours

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PubMed Central

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oai:pubmedcentral.nih.gov:3170224Last time updated on 7/8/2012View original full text link

This paper was published in PubMed Central.

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