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Clusters of Conserved Beta Cell Marker Genes for Assessment of Beta Cell Phenotype

By Geert A. Martens, Lei Jiang, Karine H. Hellemans, Geert Stangé, Harry Heimberg, Finn C. Nielsen, Olivier Sand, Jacques Van Helden, Frans K. Gorus and Daniel G. Pipeleers
Topics: Research Article
Publisher: Public Library of Science
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Provided by: PubMed Central

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  1. (1989). A
  2. (2004). A gene atlas of the mouse and human protein-encoding transcriptomes.
  3. (2010). A genomicbased approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gammaa as a pancreatic beta cell-specific biomarker.
  4. (2006). A glucose sensor role for glucokinase in anterior pituitary cells.
  5. (2002). Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes.
  6. (2004). An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene Expression (SAGE).
  7. (2007). ATF-2 stimulates the human insulin promoter through the conserved CRE2 sequence.
  8. (2003). Computational detection of cis -regulatory modules.
  9. (2006). Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft.
  10. (2004). CREME: Cis-Regulatory Module Explorer for the human genome.
  11. (2008). Defining diversity, specialization, and gene specificity in transcriptomes through information theory.
  12. (2001). DeltaFosB: a sustained molecular switch for addiction.
  13. (2010). Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program.
  14. (2009). Detailed transcriptome atlas of the pancreatic beta cell.
  15. (2002). Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis.
  16. (1997). Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer.
  17. (1998). Extracting regulatory sites from the upstream region of yeast genes by computational analysis of oligonucleotide frequencies.
  18. (2004). Extrapancreatic insulin-producing cells in multiple organs in diabetes.
  19. (2008). Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection.
  20. (2006). Genetic networks controlling the development of midbrain dopaminergic neurons.
  21. (2007). Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.
  22. (2001). Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus.
  23. (2000). Glucose-dependent insulin release from genetically engineered K cells.
  24. (2009). Glucose, regulator of survival and phenotype of pancreatic Beta cells.
  25. (1985). Gut associated lymphoid tissue: a morphological and immunocytochemical study of the human appendix.
  26. (2009). How to make beta cells? Curr Opin Cell Biol.
  27. (1999). Identification and characterization of glucoresponsive neurons in the enteric nervous system.
  28. (2004). Identification of tissue-restricted transcripts in human islets.
  29. (1999). Identifying DNA and protein patterns with statistically significant alignments of multiple sequences.
  30. (2009). Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury.
  31. (2010). Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6.
  32. (2005). Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes.
  33. (2001). Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection.
  34. (2002). Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity.
  35. (2004). Neuronal traits are required for glucose-induced insulin secretion.
  36. (2008). On the origin of the beta cell.
  37. (2004). Plasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal.
  38. (2010). Protein markers for insulin-producing beta cells with higher glucose sensitivity.
  39. (2010). Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice.
  40. (2007). Release of glutamate decarboxylase-65 into the circulation by injured pancreatic islet betacells.
  41. (2009). Retrieve-ensembl-seq: userfriendly and large-scale retrieval of single or multi-genome sequences from Ensembl.
  42. (2007). Specificity in Beta Cell Expression of L-3-Hydroxyacyl-CoA Dehydrogenase, Short Chain, and Potential Role in Down-regulating Insulin Release.
  43. (2004). ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.
  44. (1991). Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves.
  45. (2007). The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes.
  46. (2008). The mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3 null mouse. Diabetes. Beta Cell Genes Conserved from Rodents to Humans PLoS
  47. (1999). The NeuroD1/ BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding.
  48. (2001). The roles of ATF3 in glucose homeostasis. A transgenic mouse model with liver dysfunction and defects in endocrine pancreas.
  49. (2007). Transcription factors in pancreatic development. Animal models.
  50. (2004). Transcriptional networks controlling pancreatic development and beta cell function.
  51. (1991). Transplantation of purified islet cells in diabetic rats. I. Standardization of islet cell grafts.
  52. (2008). Using RSAT to scan genome sequences for transcription factor binding sites and cisregulatory modules.