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Magnetic resonance imaging of bilateral mesial temporal sclerosis in chronic kernicterus

By Virginia C. Mendes, Fernando Costa, Antónia Silva and Maria José Rosas


Kernicterus is an encephalopathy resulting from the cerebral deposition of unconjugated bilirubin in the neonatal period. We report a case of kernicterus where MRI demonstrated bilateral symmetric high signal intensity and volume loss in the hippocampus in addition to globus pallidus and subthalamic nucleus hyperintensity onT2-weighted images. The authors believe that hippocampal sclerosis, plays a role in adding specificity to the imaging diagnosis of kernicterus

Topics: Neuroimaging
Publisher: Medknow Publications
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Provided by: PubMed Central
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