Article thumbnail

P16 and Ki67 Immunostains Decrease Intra- and Interobserver Variability in the Diagnosis and Grading of Anal Intraepithelial Neoplasia (AIN)

By Ann E. Walts, Juan Lechago, Bing Hu, MaryBeth Shwayder, Lynn Sandweiss and Shikha Bose
Topics: Original Research
Publisher: Libertas Academica
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (1990). A modiļ¬ ed terminology for cervical intraepithelial neoplasia.
  2. (2007). Anal intraepithelial neoplasia and other neoplastic precursor lesions of the anal canal and perianal region.
  3. (2000). Anal squamous intraepithelial lesions in human immunodeficiency virus-positive men and women.
  4. (2002). Bethesda System: terminology for reporting results of cervical cytology.
  5. (1982). Correlates of homosexual behavior and the incidence of anal cancer.
  6. (1981). Dysplastic changes in the anal canal epithelium in minor surgical specimens.
  7. (2001). Effect of highly active antiretroviral therapy on the natural history of anal squamous intraepithelial lesions and anal human papillomavirus infection.
  8. (1998). Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions.
  9. (1994). High incidence of anal cancer among AIDS patients. The AIDS/Cancer working group.
  10. (1998). High incidence of anal high-grade squamous intraepithelial lesions among HIVss-positive and HIV-negative homosexual and bisexual men. AIDS,
  11. (2004). Human papillomavirus, smoking and sexual practices in the etiology of anal cancer.
  12. (2005). Interobserver agreement in the interpretation of anal intraepithelial neoplasia.
  13. (2003). Interobserver and intraobserver bias exists in the interpretation of anal dysplasia.
  14. (2004). Interobserver variability in grading of anal intraepithelial neoplasia is reduced by MIB-1 immunostaining.
  15. (1994). Interobserver variation in the reporting of the histopathological grading of anal intraepithelial neoplasia.
  16. (1986). Intraepithelial neoplasia in the anal canal.
  17. (2003). Is anal carcinoma a HAART-related problem?
  18. (1967). Natural history of cervical intraepithelial neoplasia.
  19. (2006). P16 and Ki67 immunostaining is a useful adjunct in the assessment of biopsies for HPV-associated anal intraepithelial neoplasia (AIN.).
  20. (2006). P16 and Ki67 immunostains decrease interobserver variability in the diagnosis and grading of anal intraepithelial neoplasia
  21. (2003). Preneoplastic anal lesions and anal canal carcinoma.
  22. (1998). Spectrum of AIDS-associated malignant disorders.