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Suitable carriers for encapsulation and distribution of endostar: comparison of endostar-loaded particulate carriers

By Weijie Chen and Sanyuan Hu
Topics: Original Research
Publisher: Dove Medical Press
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Provided by: PubMed Central

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  18. (2007). Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol.
  19. Nanoparticles based on PLGA and its co-polymer: an overview.
  20. (2009). Nanoparticles evading the reticuloendothelial system: role of the supported bilayer. Biochim Biophys Acta.
  21. (2007). Nanotechnology for targeted cancer therapy. Expert Rev Anticancer Ther.
  22. (2007). Optimizing drug delivery for enhancing therapeutic efficacy of recombinant human endostatin in cancer treatment. Crit Rev Ther Drug Carrier Syst.
  23. (2005). Pharmacokinetics of His-tag recombinant human endostatin in Rhesus monkeys. Acta Pharmacol Sin.
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  27. Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles.
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  29. (1998). Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment.
  30. (2003). Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog Lipid Res.
  31. Strategies in the design of nanoparticles for therapeutic applications. Nat Rev Drug Discov.
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  33. Targeting nanoparticles to cancer. Pharmacol Res.
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