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Redesigning a large school-based clinical trial in response to changes in community practice

By Lynn B Gerald, Joe K Gerald, Leslie A McClure, Kathy Harrington, Sue Erwin and William C Bailey

Abstract

Background Asthma exacerbations are seasonal with the greatest risk in elementary-age students occurring shortly after returning to school following summer break. Recent research suggests that this seasonality in children is primarily related to viral respiratory tract infections. Regular hand washing is the most effective method to prevent the spread of viral respiratory infections; unfortunately, achieving hand washing recommendations in schools is difficult. Therefore, we designed a study to evaluate the effect of hand sanitizer use in elementary schools on exacerbations among children with asthma

Topics: Design
Publisher: SAGE Publications
OAI identifier: oai:pubmedcentral.nih.gov:3145214
Provided by: PubMed Central

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