Article thumbnail

Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain

By Sumihisa Orita, Tetsuhiro Ishikawa, Masayuki Miyagi, Nobuyasu Ochiai, Gen Inoue, Yawara Eguchi, Hiroto Kamoda, Gen Arai, Tomoaki Toyone, Yasuchika Aoki, Takekazu Kubo, Kazuhisa Takahashi and Seiji Ohtori
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:3142251
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles

Citations

  1. (1995). al: Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons.
  2. (1995). al: Presence or absence of TrkA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections.
  3. (2006). al: Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia. Osteoarthritis Cartilage
  4. (2003). al: Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetateinduced osteoarthritis. Osteoarthritis Cartilage
  5. (2003). Aloe L: Nerve growth factor release by human synovial fibroblasts prior to and following exposure to tumor necrosis factor-alpha, interleukin-1 beta and cholecystokinin-8: the possible role of NGF in the inflammatory response. Clin Exp Rheumatol
  6. (1992). Calcitonin gene-related peptide, substance P and GAP43/B-50 immunoreactivity in the normal and arthritic knee joint of the mouse. Histochemistry
  7. (2008). Castro-Lopes JM: Assessment of movementevoked pain in osteoarthritis by the knee-bend and CatWalk tests: a clinically relevant study.
  8. (2008). Differences in innervation and innervated neurons between hip and inguinal skin. Clin Orthop Relat Res
  9. (2000). et al: Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury. Mol Cell Neurosc
  10. (2000). et al: Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: a novel neuronal marker of nerve injury. Mol Cell Neurosci
  11. (2004). et al: Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization.
  12. (2009). et al: Detection of pain-related molecules in the subchondral bone of osteoarthritic knees. Clin Rheumatol
  13. (2007). et al: Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis. Osteoarthritis Cartilage
  14. (1996). et al: Immunohistochemical analysis of an equine model of synovitis-induced arthritis.
  15. (1997). et al: Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor. Science
  16. (2004). et al: Pain related behaviour in two models of osteoarthritis in the rat knee. Pain
  17. (2003). et al: Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats.
  18. (2002). et al: TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurons. Neuropharmacol
  19. (1993). G: ’Mirror pain’ in the formalin test: behavioral and 2-deoxyglucose studies. Pain
  20. (2002). G: Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) in human osteoarthritic chondrocytes. Rheumatology (Oxford)
  21. (2007). Goldring SR: Osteoarthritis.
  22. (1991). Guerne PA: Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA).
  23. (2009). HJ: Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB in a rat neuropathic pain model.
  24. (2005). Inflammatory status and cartilage regenerative potential of synovial fibroblasts from patients with osteoarthritis and chondropathy. Rheumatology
  25. (1991). Interleukin-6 enhances the expression of tumor necrosis factor receptors on hepatoma cells and hepatocytes. Cytokine
  26. (2004). Isolectin B4 binding neurons are not present in the rat knee joint. Neuroscience
  27. (2003). LS: Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons.
  28. (2006). McMahon SB: Neurotrophins: mediators and modulators of pain. Annu Rev Neurosci
  29. (1998). McMahon SB: Tackling pain at the source: new ideas about nociceptors. Neuron
  30. (2004). MJ: The monosodium iodoacetate model of osteoarthritis: a model of chronic nociceptive pain in rats? Neurosci Lett
  31. (2006). Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide. Arthritis Rheum
  32. (1997). Monoiodoacetate-induced experimental osteoarthritis: a dose-response study of loss of mobility, morphology, and biochemistry. Arthritis Rheum
  33. (2003). Monoiodoacetateinduced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis. Toxicol Pathol
  34. (2005). MW: Neuropathic pain and spinal microglia: a big problem from molecules in “small” glia. Trends Neurosci
  35. (2000). Myers RR: Injury to dorsal root ganglia alters innervation of spinal cord dorsal horn lamina involved in nociception. Spine
  36. (1994). Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience
  37. (1991). Neurofilament immunoreactivity in populations of rat primary afferent neurons: a quantitative study of phosphorylated and non-phosphorylated subunits.
  38. (1997). Neurophysiology of nociception and pain reactions in inflammatory joint diseases. Rev Rhum Engl Ed
  39. (2004). NGF and GDNF ameliorate the increase in ATF3 expression which occurs in dorsal root ganglion cells in response to peripheral nerve injury.
  40. (2005). Raczyńska-Witońska G: Distribution of substance P nerve fibers in osteoarthritis knee joint.
  41. (2005). Regulation of calcitonin generelated peptide and TRPV1 in a rat model of osteoarthritis. Neurosci Lett
  42. (2004). RR: TNF-α and TNF-α receptor type 1 upregulation in glia and neurons after peripheral nerve injury: studies in murine DRG and spinal cord. Spine
  43. (2002). SA: Induction of osteoarthritis in the rat by surgical tear of the meniscus: inhibition of joint damage by a matrix metalloproteinase inhibitor. Osteoarthritis Cartilage
  44. (1999). SB: Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin.
  45. (2001). SF: Glial activation: a driving force for pathological pain. Trends Neurosci
  46. (2007). SJ: Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF3 and pharmacological characterisation. Pain
  47. (1997). Synovial membrane inflammation and cytokine production in patients with early osteoarthritis.