Article thumbnail

Heart Rate Variability and Atria Function in Children at Late Follow-Up Evaluation After Atrioventricular Node Slow-Pathway Radiofrequency Ablation

By Rima Sileikiene, Jolanta Vaskelyte, Vaida Mizariene, Irena Nedzelskiene, Raimonda Verseckaite, Renaldas Jurkevicius, Dalia Baksiene, Viktorija Sileikyte and Rimantas Kevalas

Abstract

This study was designed to assess the changes in the conductive system, autonomic dysfunction, and global and regional function of the atria and ventricles in children late after slow-pathway radiofrequency ablation (RFA). The study enrolled 22 children, who has successfully undergone RFA 2 to 5 years previously (RFA group) and 20 healthy children (control group). Electrophysiologic study was performed for the RFA group. Holter monitoring and echocardiography were performed for all the children. At a late follow-up assessment, the RFA children were free of paroxysms, whereas 8 of the 22 children (36%) reported transient palpitations. Both mean and maximal heart rates (HR) were significantly increased, whereas indices of HR variability (% of succesive normal sinus RR intervals exceeding 50 ms [pNN50], root mean square of the succesive normal sinus RR interval difference [rMSSD], high-frequency component [HFC]) were significantly decreased in the RFA group compared with preablation and control data. Left atrial (LA) and right atrial (RA) volumes were significantly higher, and atria deformation indices were significantly lower in the RFA group. Correlations were found between the mean HR and the volumes of LA (r = 0.477; p < 0.001) and RA (r = 0.512; p < 0.001). A negative correlation between the maximal LA volume and the longitudinal strain rate (SR) during relaxation (r = –0.476; p = 0.03) and a positive correlation between the minimal LA volume and both longitudinal SR (r = 0.361; p = 0.03) and strain (ε) (r = 0.375; p = 0.024) during contraction were shown. These data suggest a possible link between atrial dysfunction and the hyperadrenergic state after RFA

Topics: Original Article
Publisher: Springer-Verlag
OAI identifier: oai:pubmedcentral.nih.gov:3139060
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles

Citations

  1. (1993). Alterations of heart rate and of heart rate variability after radiofrequency catheter ablation of supraventricular tachycardia.
  2. (2005). American Society of Echocardiography’s Nomenclature, Standards Committee; Task Force on Chamber Quantification; American College of Cardiology Echocardiography Committee; American Heart Association; European Association of Echocardiography,
  3. (2006). Analysis of myocardial deformation based on pixel tracking in 2D echocardiographic images allows quantitative assessment of regional left ventricular function.
  4. (2008). Assessment of regional atrial function in patients with hypertrophic cardiomyopathies using tissue Doppler imaging.
  5. (2008). Atrial mycardial deformation properties in obese nonhypertensive children.
  6. (2002). Atrioventricular nodal reentrant tachycardia in children: effect of slow-pathway ablation on fast-pathway function.
  7. (1997). Bayes de Luna A
  8. (1996). Complications of diagnostic electrophysiological studies and radiofrequency catheter ablation in patients with tachyarrhythmias: an eight-year survey 3, 966 consecutive procedures in a tertiary referral center.
  9. (2007). Delayed injury of autonomic nerve induced by radiofrequency catheter ablation.
  10. (1999). Effect of radiofrequency catheter ablation of accessory pathways on autonomic tone in children. Cardiol Young 9:377–383
  11. (1994). Efficacy and safety of radiofrequency ablation in infants and young children\18 months of age.
  12. (2006). Feasibility of strain and strain rate imaging for the assessment of regional left atrial deformation: a study in normal subjects.
  13. (1994). Late enlargement of radiofrequency lesions in infant lambs: implications for ablation procedures in small children.
  14. (2007). Left ventricular form and function revisited: applied translation science to cardiovascular ultrasound imaging.
  15. (1998). Livanis EG, DTh Kremastinos
  16. (2004). Myocardial remodeling after discrete radiofrequency injury: effects of tissue inhibitor of matrix metalloproteinase-1 gene deletion.
  17. (2010). New-onset postural orthostatic tachycardia syndrome following ablation of AV node reentrant tachycardia.
  18. (2007). Principles and different techniques for speckle tracking. In: Marwick TH, ChM Yu, Sun JP (eds) Myocardial imaging tissue Doppler and speckle tracking
  19. (1996). Task force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology
  20. (2002). the other participating members of the pediatric radiofrequency ablation registry of the Pediatric Electrophysiology Society
  21. (2009). Two-dimensional speckle-tracking echocardiography of the left atrium: feasibility and regional contraction and relaxation differences in normal subjects. J Am Soc Echo 22:299–305 800 Pediatr Cardiol
  22. (2009). Two-dimensional strain and atrial function: a study on patients after percutaneous closure of atrial septal defect.