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Ras Signaling in Yeast

By Fuyuhiko Tamanoi

Abstract

Since the study of yeast RAS and adenylate cyclase in the early 1980s, yeasts including budding and fission yeasts contributed significantly to the study of Ras signaling. First, yeast studies provided insights into how Ras activates downstream signaling pathways. Second, yeast studies contributed to the identification and characterization of GAP and GEF proteins, key regulators of Ras. Finally, the study of yeast provided many important insights into the understanding of C-terminal processing and membrane association of Ras proteins

Topics: Monographs
Publisher: SAGE Publications
OAI identifier: oai:pubmedcentral.nih.gov:3128628
Provided by: PubMed Central
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