Article thumbnail

Exacerbation of cigarette smoke-induced pulmonary inflammation by Staphylococcus aureus Enterotoxin B in mice

By Wouter Huvenne, Ellen A Lanckacker, Olga Krysko, Ken R Bracke, Tine Demoor, Peter W Hellings, Guy G Brusselle, Guy F Joos, Claus Bachert and Tania Maes
Topics: Research
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (1999). Airway exposure to bacterial superantigen (SEB) induces lymphocyte-dependent airway inflammation associated with increased airway responsiveness - a model for non-allergic asthma.
  2. (1996). Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils. Thorax
  3. (2008). al: IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am J Respir Crit Care Med
  4. (2007). al: IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance.
  5. (2010). al: Staphylococcus aureus enterotoxin B facilitates allergic sensitization in experimental asthma. Clin Exp Allergy
  6. (2008). AT: Inhalation of Staphylococcus aureus enterotoxin A induces IFN-gamma and CD8 T cell-dependent airway and interstitial lung pathology in mice.
  7. (2008). AT: Recruitment and in situ renewal regulate rapid accumulation of CD11c+ cells in the lung following intranasal superantigen challenge. Int Arch Allergy Immunol
  8. (2002). B: Inhibition of mediator and cytokine release from dispersed nasal polyp cells by mizolastine. Allergy
  9. (2009). Brusselle GG: CCR7 modulates pulmonary and lymph node inflammatory responses in cigarette smoke-exposed mice.
  10. (2006). Brusselle GG: Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice.
  11. (2009). Brusselle GG: Role of lymphotoxin-alpha in cigarette smoke-induced inflammation and lymphoid neogenesis. Eur Respir J
  12. (2006). C: Aggravation of bronchial eosinophilia in mice by nasal and bronchial exposure to Staphylococcus aureus enterotoxin B. Clin Exp Allergy
  13. (2004). C: Increased IgE-antibodies to Staphylococcus aureus enterotoxins in patients with COPD. Respir Med
  14. (2007). C: Local immunoglobulin production in nasal polyposis is modulated by superantigens. Clin Exp Allergy
  15. (2001). Cauwenberge P: Total and specific IgE in nasal polyps is related to local eosinophilic inflammation.
  16. (2009). E, et al: Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome. Nat Med
  17. (2003). Geha RS: Epicutaneous sensitization with superantigen induces allergic skin inflammation. J Allergy Clin Immunol
  18. (2008). Gevaert P: Role of staphylococcal superantigens in upper airway disease. Curr Opin Allergy Clin Immunol
  19. (2005). JL: The role of nasal carriage in Staphylococcus aureus infections. Lancet Infect Dis
  20. (2007). Mariuzza RA: TCR recognition of peptide/MHC class II complexes and superantigens. Semin Immunol
  21. (2009). Migration and function of Th17 cells. Inflamm Allergy Drug Targets
  22. (2004). Monasterolo G: Prevalence of serum IgE antibodies to the Staphylococcus aureus enterotoxins (SAE, SEB, SEC, SED, TSST-1) in patients with persistent allergic rhinitis. Int Arch Allergy Immunol
  23. (2005). Neutrophils, interleukin-17A and lung disease. Eur Respir J
  24. (2003). Pauwels RA: Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J
  25. (2007). Perez-Novo C: Role of staphylococcal superantigens in airway disease. Chem Immunol Allergy
  26. (2009). PJ: Impairing oral tolerance promotes allergy and anaphylaxis: a new murine food allergy model. J Allergy Clin Immunol
  27. (2008). Proft T: The bacterial superantigen and superantigen-like proteins. Immunol Rev
  28. (2010). PW: Staphylococcus aureus enterotoxin B augments granulocyte migration and survival via airway epithelial cell activation. Allergy
  29. (2002). SA: Ectopic expression of the murine chemokines CCL21a and CCL21b induces the formation of lymph node-like structures in pancreas, but not skin, of transgenic mice.
  30. (2009). Salek-Ardakani S: Regulation of TH17 cells in the mucosal surfaces.
  31. (2007). Spadaro G: Role of superallergens in allergic disorders. Chem Immunol Allergy
  32. (2007). Stampfli MR: Animal models of chronic obstructive pulmonary disease exacerbations. Contrib Microbiol
  33. (2009). Stampfli MR: Bacteria challenge in smoke-exposed mice exacerbates inflammation and skews the inflammatory profile. Am J Respir Crit Care Med
  34. (2004). Stampfli MR: Impact of cigarette smoke on clearance and inflammation after Pseudomonas aeruginosa infection. Am J Respir Crit Care Med
  35. (2003). Staphylococcal enterotoxin induced IL-5 stimulation as a cofactor in the pathogenesis of atopic disease: the hygiene hypothesis in reverse? Allergy
  36. (2008). TF: Infection in the pathogenesis and course of chronic obstructive pulmonary disease.
  37. (1977). The natural history of chronic airflow obstruction. Br Med J
  38. (2001). Werfel T: Bacterial infections and atopic dermatitis. Allergy
  39. (1999). Zaubet A: Airway inflammation and bronchial microbial patterns in patients with stable chronic obstructive pulmonary disease. Eur Respir J