Article thumbnail

SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer

By Megana K Prasad, Xylena Reed, David U Gorkin, Julia C Cronin, Anthony R McAdow, Kristopher Chain, Chani J Hodonsky, Erin A Jones, John Svaren, Anthony Antonellis, Stephen L Johnson, Stacie K Loftus, William J Pavan and Andrew S McCallion
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:3124416
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles

Citations

  1. (2011). A unique chromatin signature uncovers early developmental enhancers in humans. Nature
  2. (2006). A: Deletion of long-range sequences at Sox10 compromises developmental expression in a mouse model of Waardenburg-Shah (WS4) syndrome. Hum Mol Genet
  3. (1995). A: Heregulindependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3.
  4. (2007). al: Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet
  5. (1997). Birchmeier C: Severe neuropathies in mice with targeted mutations in the ErbB3 receptor. Nature
  6. (1994). Cerione RA: The erbB3 gene product is a receptor for heregulin.
  7. (2001). Chakravarti A: EDNRB/EDN3 and Hirschsprung disease type II. Pigment Cell Res
  8. (2006). Chromatin immunoprecipitation and microarray-based analysis of protein location. Nat Protoc
  9. (1988). Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. Genes Dev
  10. (2002). DC: p16(Ink4a) in melanocyte senescence and differentiation.
  11. (2005). et al: Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res
  12. (2010). et al: Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci USA
  13. (2008). et al: Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish. PLoS Genet
  14. (1998). et al: SOX10 mutations in patients with Waardenburg-Hirschsprung disease. Nat Genet
  15. (2001). FE: A family of AP-2 proteins down-regulate manganese superoxide dismutase expression.
  16. (2002). FE: Dominant negative interference of transcription factor AP-2 causes inhibition of ErbB-3 expression and suppresses malignant cell growth. Breast Cancer Res Treat
  17. (2005). GP: ErbB receptors mediate both migratory and proliferative activities in human melanocytes and melanoma cells. Melanoma Res
  18. (1993). HC: Transcriptional regulation of the c-erbB-3 gene in human breast carcinoma cell lines. Oncogene
  19. (1997). Isoform-specific expression and function of neuregulin. Development
  20. (2008). JS: Neuregulin-mediated ErbB3 signaling is required for formation of zebrafish dorsal root ganglion neurons. Development
  21. (2001). Kelsh RN: A morpholino phenocopy of the colourless mutant. Genesis
  22. (2008). Kelsh RN: An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10. BMC Dev Biol
  23. (2001). Kelsh RN: Zebrafish colourless encodes sox10 and specifies non-ectomesenchymal neural crest fates. Development
  24. (1994). KL: Insect cellexpressed p180erbB3 possesses an impaired tyrosine kinase activity.
  25. (1995). LC: Heregulin stimulates mitogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3.
  26. (2005). MatInspector and beyond: promoter analysis based on transcription factor binding sites. Bioinformatics
  27. (2006). McCallion AS: Conservation of RET regulatory function from human to zebrafish without sequence similarity. Science
  28. (2006). McCallion AS: Evaluating the biological relevance of putative enhancers using Tol2 transposon-mediated transgenesis in zebrafish. Nat Protoc
  29. (2004). Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations. Nat Genet
  30. (2004). Molecular mechanisms of neural crest induction. Birth Defects Res C Embryo Today
  31. (1998). Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. Proc Natl Acad Sci USA
  32. (1997). MW: ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice. Development
  33. (2008). Parichy DM: Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation. Development
  34. (1996). PJ: Transcription factor AP-2 essential for cranial closure and craniofacial development. Nature
  35. (2011). Regulation of the PMP22 Gene through an Intronic Enhancer.
  36. (1994). RH: Biochemical and cellular properties of three immortalized Schwann cell lines expressing different levels of the myelin-associated glycoprotein.
  37. (2001). S: Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat Genet
  38. (1995). Schilling TF: Stages of embryonic development of the zebrafish. Dev Dyn
  39. (1998). Sox10, a novel transcriptional modulator in glial cells.
  40. (2009). Swain SM: Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nat Rev Cancer
  41. (1996). T: Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature
  42. (1998). The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system. Genes Dev
  43. (2007). The neuregulin-I/ErbB signaling system in development and disease. Adv Anat Embryol Cell Biol
  44. (2001). The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev
  45. (2000). The Zebrafish Book. A guide for the laboratory use of zebrafish (Danio rerio).
  46. (1989). Tjian R: Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers. Genes Dev
  47. (1991). Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev
  48. (2009). WJ: NRG1/ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation. Pigment Cell Melanoma Res
  49. (2008). WJ: Transcriptional and signaling regulation in neural crest stem cell-derived melanocyte development: do all roads lead to Mitf? Cell Res
  50. (2005). WS: erbb3 and erbb2 are essential for schwann cell migration and myelination in zebrafish. Curr Biol