Article thumbnail

Rapid screening for chromosomal aneuploidies using array-MLPA

By Jing-Bin Yan, Miao Xu, Can Xiong, Da-Wen Zhou, Zhao-Rui Ren, Ying Huang, Monique Mommersteeg, Rinie van Beuningen, Ying-Tai Wang, Shi-Xiu Liao, Fanyi Zeng, Ying Wu and Yi-Tao Zeng
Topics: Technical Advance
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (2006). Armour JA: Microarray MAPH: accurate array-based detection of relative copy number in genomic DNA. BMC Genomics
  2. (2008). Array-MLPA: comprehensive detection of deletions and duplications and its application to DMD patients. Hum Mutat
  3. (2002). Assche FA, Fryns JP: Rapid prenatal diagnosis of trisomy 21 in 5049 consecutive uncultured amniotic fluid samples by fluorescence in situ hybridisation (FISH). Prenat Diagn
  4. (2001). CM: Development and implementation of a new rapid aneuploidy diagnostic service within the UK National health service and implications for the future of prenatal diagnosis. Lancet
  5. (2004). CM: Strategies for the rapid prenatal diagnosis of chromosome aneuploidy.
  6. (2007). Complete discrepancy between QF-PCR analysis of uncultured villi and karyotyping of cultured cells in theprenatal diagnosis of trisomy 21 in three CVS. Prenat Diagn
  7. (1992). Dackowski W: Rapid detection of chromosome aneuploidies in uncultured amniocytes by using fluorescence in situ hybridization (FISH).
  8. (2005). den Dunnen JT: Deletion and duplication screening in the DMD gene using MLPA.
  9. (1991). Detection of aneuploidy involving chromosomes 13, 18 or 21, by fluorescence in situ hybridization (FISH) to interphase and metaphase amniocytes.
  10. (1993). Diagnosis of Down syndrome and other aneuploidies using quantitative polymerase chain reaction and small tandem repeat polymorphisms. Hum Mol Genet
  11. (2005). Flinter F: The future of prenatal diagnosis: rapid testing or full karyotype? An audit of chromosome abnormalities and pregnancy outcomes for women referred for Down’s Syndrome testing. BJOG
  12. (2002). G: Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification. Nucleic Acids Res
  13. (2009). Galjaard RJ: Rapid aneuploidy detection with multiplex ligation-dependent probe amplification: a prospective study of 4000 amniotic fluid samples.
  14. (2004). GR: MLPA and MAPH: new techniques for detection of gene deletions. Hum Mutat
  15. (2000). Kalousek DK: Comparative genomic hybridization in combination with flow cytometry improves results of cytogenetic analysis of spontaneous abortions.
  16. (2003). KH: Rapid, high throughput prenatal detection of aneuploidy using a novel quantitative method (MLPA).
  17. (2001). Kievits T: Fast and specific hybridisation using flow-through microarrays on porous metal oxide. Clin Chem
  18. (1993). KW: Rapid prenatal diagnosis of chromosomal aneuplodies by fluorescence in situ hybridisation: clinical experience with 4500 specimens.
  19. (2009). LJ: An international system for human cytogenetic nomenclature.
  20. (2004). Naeem R: Cytogenetic abnormalities in products of conception: A relationship revisited.
  21. (2005). PC: Nine unknown rearrangements in 16p13.3 and 11p15.4 causing alpha- and beta-thalassaemia characterised by high resolution multiplex ligation-dependent probe amplification.
  22. (1995). Pertl B: Rapid detection of selected aneuploidies by quantitative fluorescent PCR. Bioessays
  23. (2005). Ploos van Amstel JK, de Pater JM: Rapid detection of chromosomal aneuploidies in uncultured amniocytes by multiplex ligation-dependent probe amplification (MLPA). Prenat Diagn
  24. (1994). Prenatal aneuploidy detection in interphase cells by fluorescence in siu hybridization (FISH). Prenat Diagn
  25. (2004). Quantitative assessment of a novel flow-through porous microarray for the rapid analysis of gene expression profiles. Nucleic Acids Res
  26. (2006). Rapid prenatal diagnosis by QF-PCR: evaluation of 30,000 consecutive clinical samples and future applications.
  27. (2004). Rapid prenatal diagnosis of common chromosome aneuploidies by QF-PCR. Assessment on 18,000 consecutive clinical samples. Mol Hum Reprod
  28. (2009). Slater HR: Development of a multiplex ligation-dependent probe amplification assay for diagnosis and estimation of the frequency of spinocerebellar ataxia type 15. Clin Chem
  29. (2005). Stuppia L: Identification of deletions and duplications of the DMD gene in affected males and carrier females by multiple ligation probe amplification (MLPA). Hum Genet
  30. (2002). X chromosome dosage by quantitative fluorescent PCR and rapid prenatal diagnosis of sex chromosome aneuploidies. Mol Hum Reprod