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Effective use of polymyxin B hemoperfusion in septic shock complicated by urosepsis

By P. Malleshappa, R. Ranganath, A. P. Chaudhari, P. Singhai, M. Aghariya and A. B. Shah


Direct hemoperfusion using polymyxin B–immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. Here we report one instance in which PMX-DHP therapy has been used successfully in a patient with septic shock from urosepsis. After antibiotic therapy, direct hemoperfusion using polymyxin B helped in cardiovascular stability. The patient recovered from the shock within a few days after treatment with polymyxin-B hemoperfusion. As far as we are aware, this is the first reported case of effective treatment of urosepsis complicated by septic shock using PMX-DHP therapy in India

Topics: Case Report
Publisher: Medknow Publications
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Provided by: PubMed Central
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