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Rod Outer Segment Retinol Formation Is Independent of Abca4, Arrestin, Rhodopsin Kinase, and Rhodopsin Palmitylation

By Lorie R. Blakeley, Chunhe Chen, Ching-Kang Chen, Jeannie Chen, Rosalie K. Crouch, Gabriel H. Travis and Yiannis Koutalos


All-trans retinol is formed in rod photoreceptor outer segments through the reduction of the reactive aldehyde all-trans retinal released from photoactivated rhodopsin. This work examines the dependence of all-trans retinol formation on biochemical factors that affect the release and sequestration of all-trans retinal

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Publisher: Association for Research in Vision and Ophthalmology, Inc.
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