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Selected luminal mucosal complications of adult celiac disease

By Hugh J Freeman


Celiac disease is a gluten-dependent intestinal disorder that appears to be associated with several clinical conditions. Some involve the luminal mucosa of the stomach and intestinal tract and may, occasionally, complicate the course of celiac disease. Collagenous colitis has been associated with celiac disease and may lead to chronic diarrhea. Conversely, some of these clinical disorders that involve the luminal mucosa of the stomach and intestine may represent the initial clinical presentation of celiac disease. These disorders should be considered in patients with celiac disease who develop recurrent or refractory symptoms despite adherence to a strict gluten-free diet. Detection of collagenous disorders that affect the luminal mucosa of the stomach or intestinal tract may result in recognition of underlying celiac disease

Topics: Review
Publisher: Dove Medical Press
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Provided by: PubMed Central

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  1. (1985). An evaluation of the signifi cance of microscopic colitis in patients with chronic diarrhea.
  2. (1999). antiendomysial antibodies and lymphocytic colitis in collagenous sprue.
  3. (1999). Cancer risk in collagenous colitis. Infl amm Bowel Dis.
  4. Cat scratch colon.
  5. (2003). Changing presentation of adult celiac disease. Dig Dis Sci.
  6. (1990). Coeliac disease and collagenous colitis. Postgrad Med J.
  7. (2002). Collagenous and lymphocytic colitis in Iceland. Dig Dis.
  8. Collagenous colitis as the presenting feature of biopsydefi ned celiac disease.
  9. (1986). Collagenous colitis associated with small intestinal villous atrophy.
  10. Collagenous colitis in children: clinicopathologic, microbiologic, and immunologic factors.
  11. (1976). Collagenous colitis with watery diarrhea – a new entity? Pathol Eur.
  12. (1992). Collagenous colitis: jejunal and colorectal pathology.
  13. (1995). Collagenous colitis: mucosal biopsies and association with fecal leukocytes. Mayo Clin Proc.
  14. (1992). Collagenous enterocolitis: a manifestation of gluten-sensitive enteropathy.
  15. (2001). Collagenous gastritis associated with lymphocytic gastritis and celiac disease. Arch Pathol Lab Med.
  16. (1989). Collagenous gastritis.
  17. Collagenous mucosal inflammatory diseases of the gastrointestinal tract.
  18. Collagenous sprue – an unrecognized type of malabsorption.
  19. Collagenous sprue associated with an extensive T-cell lymphoma.
  20. (1990). Colonic lymphocytosis in patients with celiac sprue. Hum Pathol.
  21. Complete histological resolution of collagenous sprue.
  22. (1988). Concurrent collagenous colitis and multiple ileal carcinoids. Dig Dis Sci.
  23. Endoscopic and histologic fi ndings in the duodenum of adults with celiac disease before and after changing to a gluten-free diet: a 2-year prospective study.
  24. Evolution of collagenous colitis into severe and extensive ulcerative colitis.
  25. Fractured colon: an endoscopically distinctive lesion associated with colonic perforation following colonoscopy in patients with collagenous colitis.
  26. (1996). Functional asplenia and microscopic (collagenous) colitis.
  27. (1990). Lymphocytic gastritis in patients with celiac sprue or sprue-like intestinal disease.
  28. Lymphoproliferative and intestinal malignancies in 214 patients with biopsy-defi ned celiac disease.
  29. Lymphoproliferative disorders in collagenous colitis. Infl amm Bowel Dis.
  30. (1993). Microscopic colitis: a common diarrheal disease. An epidemiological study in Orebro,
  31. Pancreatic endocrine and exocrine changes in celiac disease.
  32. Pearls and pitfalls in the diagnosis of adult celiac disease.
  33. Predisposing HLADQ2 and HLA-DQ8 haplotypes of celiac disease and associated enteropathy in microscopic colitis.
  34. Prevalence of celiac disease in collagenous and lymphocytic colitis.
  35. Refractory sprue, celiac disease, and enteropathy-associated T-cell lymphoma.
  36. Resolution of paraneoplastic collagenous enterocolitis after resection of colon cancer.
  37. (1975). Small intestinal biopsy. Hum Pathol.
  38. Spontaneous peritonitis from perforation of the colon in collagenous colitis.
  39. Studies of celiac sprue. IV. The response of the whole length of the small bowel to a gluten-free diet.
  40. Submucosal “dissection” in collagenous colitis.
  41. Synchronous collagenous sprue and enteropathy-associated T-cell lymphoma.
  42. (1992). T-cell mediated intestinal injury.
  43. The histologic spectrum and clinical outcome of refractory and unclassifi ed sprue.
  44. Topographic mapping of collagenous gastritis.
  45. (1976). Watery diarrhea syndrome associated with a lesion of the colonic basement membrane-lamina propria interface. Ann Roy Coll Phys Surg Can.